2019 Winston-Salem Open
The 2019 Winston-Salem Open was a men's tennis tournament played on outdoor hard courts. It was the 51st edition of the Winston-Salem Open (as successor to previous tournaments in New Haven and Long Island), and part of the ATP Tour 250 Series of the 2019 ATP Tour. It took place at Wake Forest University in Winston-Salem, North Carolina, United States, from August 18 through August 24, 2019. It was the last event on the 2019 US Open Series before the 2019 US Open.
Singles main-draw entrants
Seeds
1 Rankings are as of August 12, 2019
Other entrants
The following players received wildcards into the singles main draw:
The following players received entry using a protected ranking into the singles main draw:
The following players received entry from the qualifying draw:
Withdrawals
Nikoloz Basilashvili → replaced by 
Thiago Monteiro
Borna Ćorić → replaced by 
Albert Ramos Viñolas
Pablo Cuevas → replaced by 
Tennys Sandgren
Federico Delbonis → replaced by 
Alexei Popyrin
Hugo Dellien → replaced by 
Prajnesh Gunneswaran- Bradley Klahn → replaced by Jaume Munar
Jozef Kovalík → replaced by 
Amir Weintraub
Mikhail Kukushkin → replaced by 
Lee Duck-hee
Adrian Mannarino → replaced by Denis Kudla
Yoshihito Nishioka → replaced by Antoine Hoang
Retirements
- Alexander Bublik ((Injury))
- Jérémy Chardy (Ankle injury)
Filip Krajinović ((Illness))- Feliciano López ((Unknown))
Lloyd Harris ((Unknown))
Doubles main-draw entrants
Seeds
1 Rankings are as of August 12, 2019
Other entrants
The following pairs received wildcards into the doubles main draw:
The following pair received entry as alternates:
Withdrawals
Champions
Singles
Hubert Hurkacz def. Benoît Paire, 6–3, 3–6, 6–3
Doubles
- Łukasz Kubot / Marcelo Melo def. Nicholas Monroe / Tennys Sandgren, 6–7(6–8), 6–1, [10–3]