5-HT1F receptor
5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it.
Agonists
- 5-n-Butyryloxy-DMT: >60-fold selectivity versus 5-HT1E receptor
- BRL-54443 - mixed 5-HT1E/1F agonist
- Eletriptan - mixed 5-HT1B/1D/1E/1F/2B/7 agonist
- LY-334,370 - as well as related benzamides
- LY-344,864 (N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide)
- Naratriptan - mixed 5-HT1B/1D/1F agonist
- Lasmiditan - selective 5-HT1F agonist, a first-in-class ditan molecule
Antagonists
MLS000756415
See also
References
Further reading
External links
- "5-HT1F". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
- Human HTR1F genome location and HTR1F gene details page in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.