Aminoadipate-semialdehyde dehydrogenase

AASDH
Identifiers
AliasesAASDH, ACSF4, LYS2, NRPS1098, NRPS998, aminoadipate-semialdehyde dehydrogenase
External IDsOMIM: 614365; MGI: 2442517; GeneCards: AASDH
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
1.2.1.31↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

132949

231326

Ensembl

ENSG00000157426

ENSMUSG00000055923

UniProt

Q4L235

Q80WC9

RefSeq (mRNA)

NM_173765
NM_001377004

RefSeq (protein)

NP_776126
NP_001363933

Location (UCSC)Chr 4: 56.34 – 56.39 MbChr 5: 77.02 – 77.05 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene.

Function

This gene encodes a member of the non-ribosome peptide synthetase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4'phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000157426 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000055923 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ "Entrez Gene: Aminoadipate-semialdehyde dehydrogenase". Retrieved 2017-01-02.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.