In organic chemistry, an aminomethyl group is a monovalent functional group with formula −CH2−NH2. It can be described as a methyl group substituted by an amino group −NH2. Commonly aminomethylations are the result of a Mannich reaction.
In organic chemistry, an aminomethyl group is a monovalent functional group with formula −CH2−NH2. It can be described as a methyl group substituted by an amino group −NH2. Commonly aminomethylations are the result of a Mannich reaction.
Usually aminomethyl groups feature tertiary amines. Often they are obtained by alkylation with Eschenmoser's salt, a source of [CH2=N(CH3)2]+..
A cobalt(III) complex of aminomethyl is known in the form [Co(bipyridine)2(CH2NH2)](ClO4)2.
Aminomethyl is the first member of a series of 1-aminoalkyl groups of the form −(CH2−)nNH2.
Aminomethyl is used in the standard (IUPAC) names of some compounds, such as 4-(aminomethyl) benzoic acid.