Dibutoxy ethyl phthalate

Dibutoxy ethyl phthalate
Names
Preferred IUPAC name
Bis(2-butoxyethyl) benzene-1,2-dicarboxylate
Other names
  • Bis(2-butoxyethyl) phthalate
  • Butyl glycol phthalate
  • Dibutoxyethyl phthalate
  • Dibutylglycol phthalate
  • Kesscoflex
  • Kronisol
  • Palatinol K
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.003.831 Edit this at Wikidata
EC Number
  • 204-213-1
KEGG
UNII
  • InChI=1S/C20H30O6/c1-3-5-11-23-13-15-25-19(21)17-9-7-8-10-18(17)20(22)26-16-14-24-12-6-4-2/h7-10H,3-6,11-16H2,1-2H3
    Key: CMCJNODIWQEOAI-UHFFFAOYSA-N
  • CCCCOCCOC(=O)C1=CC=CC=C1C(=O)OCCOCCCC
Properties
C20H30O6
Molar mass 366.454 g·mol−1
Appearance Colorless liquid
Density 1.06 g/cm3 (20 °C)
Melting point −55 °C (−67 °F; 218 K)
Boiling point 270 °C (518 °F; 543 K)
low
Solubility soluble in organic solvents
Vapor pressure 0.00217 mmHg
1.486 (20 °C/D)
Viscosity 42 mPa·s (20 °C)
Hazards
GHS labelling:
GHS09: Environmental hazard
Warning
H413
P273, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 1: Exposure would cause irritation but only minor residual injury. E.g. turpentineFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
1
1
0
Flash point 208 °C (406 °F; 481 K)
Lethal dose or concentration (LD, LC):
8380 mg/kg (oral rat)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Dibutoxy ethyl phthalate is an organic compound and phthalate ester, baring 2-butoxyethanol groups. Like most phthalates it is nonvolatile, and remains liquid over a wide range of temperatures. Although its water solubility is low, it remains one of the most water soluble of the common phthalates.[citation needed]

Uses

It is used as a plasticizer in polyvinyl chloride, polyvinyl acetate and cellulose acetate. It is resistant to microbial attack.

It is used to improve the collection efficiency of specialized filter papers (IP 1478) designed for bulk particulate and trace element sampling in the atmosphere.

Safety

Bis(2-butoxyethyl) phthalate exposure has been associated with reproductive toxicity and endocrine disruption.

References

  1. 1 2 PubChem. "Bis(2-butoxyethyl) phthalate". pubchem.ncbi.nlm.nih.gov. Retrieved 2026-01-27.
  2. ↑ Adelman, R. L.; Allen, G. G.; Sinclair, H. K. (1963-06-01). "Binders for Nonwoven Fabrics. Evaluation of Binders Based on Copolymers of Vinyl Acetate". I&EC Product Research and Development. 2 (2): 108–113. doi:10.1021/i360006a005. ISSN 0536-1079.
  3. ↑ Summer, W. (1964-04-01). "Microbial degradation of plastics". Anti-Corrosion Methods and Materials. 11 (4): 19–21. doi:10.1108/eb020171. ISSN 0003-5599.
  4. ↑ Gandrud, Bruce W.; Lazrus, Allan L. (2002-05-01). "Design of system for removing water-soluble materials from IPC-1478 filter paper". ACS Publications. doi:10.1021/es60064a002. Retrieved 2026-01-27.
  5. ↑ Rancitelli, L. A.; Perkins, R. W. (1970). "Trace element concentrations in the troposphere and lower stratosphere". Journal of Geophysical Research. 75 (15): 3055–3064. doi:10.1029/JC075i015p03055. ISSN 2156-2202.
  6. ↑ Yu, Jia; Zou, Haoyang; Zhang, Tiehua; Zhang, Jie (2023-11-15). "Nuclear Receptors-Mediated Endocrine Disrupting Effects of Non-Phthalate Plasticizers: A Review". Journal of Agricultural and Food Chemistry. 71 (45): 16902–16918. doi:10.1021/acs.jafc.3c04060. ISSN 0021-8561.
  7. ↑ Li, Zixuan; Robaire, Bernard (2025-02-27). "Effects of Endocrine-Disrupting Chemicals on Adrenal Function". Endocrinology. 166 (4). doi:10.1210/endocr/bqaf045. ISSN 1945-7170. PMC 11907101. PMID 40048632.