CA-105 may refer to:
- Interstate 105 (California), part of the Interstate Highway System but simply referred to as "Route 105" in state law.
- Interstate 105 (California 1964–1968), a former Interstate highway
- California State Route 105 (1968–1993), a former rump highway
- Caproni Ca.105, an experimental aircraft
This disambiguation page lists articles associated with the title CA-105.
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