Carlactone synthase

Carlactone synthase
Identifiers
EC no.1.13.11.69
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Carlactone synthase (EC 1.13.11.69, CCD8 (gene), MAX4 (gene), NCED8 (gene)) is an enzyme with systematic name 9-cis-10'-apo-beta-carotenal:O2 oxidoreductase (14,15-cleaving, carlactone-forming). This enzyme catalyses the following chemical reaction

9-cis-10'-apo-beta-carotenal + 2 O2 carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal

Carlactone synthase contains Fe2+.

References

  1. ↑ Sorefan K, Booker J, Haurogné K, Goussot M, Bainbridge K, Foo E, Chatfield S, Ward S, Beveridge C, Rameau C, Leyser O (June 2003). "MAX4 and RMS1 are orthologous dioxygenase-like genes that regulate shoot branching in Arabidopsis and pea". Genes & Development. 17 (12): 1469–74. doi:10.1101/gad.256603. PMC 196077. PMID 12815068.
  2. ↑ Schwartz SH, Qin X, Loewen MC (November 2004). "The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching". The Journal of Biological Chemistry. 279 (45): 46940–5. doi:10.1074/jbc.M409004200. PMID 15342640.
  3. ↑ Alder A, Jamil M, Marzorati M, Bruno M, Vermathen M, Bigler P, Ghisla S, Bouwmeester H, Beyer P, Al-Babili S (March 2012). "The path from β-carotene to carlactone, a strigolactone-like plant hormone". Science. 335 (6074): 1348–51. Bibcode:2012Sci...335.1348A. doi:10.1126/science.1218094. PMID 22422982. S2CID 29137583.