Charles Schaeffer may refer to:
- Charles Ashmead Schaeffer (1843–1898), President of the University of Iowa
- Charles Frederic August Schaeffer (1860–1934), American entomologist
- Charles William Schaeffer (1813–1896), American Lutheran clergyman and theologian
- Charles Frederick Schaeffer (1807–1879), American Lutheran clergyman
- Charles Schäffer (1838–1903), American physician and botanist
This disambiguation page lists articles about people with the same name.
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