Complement component 1s
Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system. C1s is part of the C1 complex. In humans, it is encoded by the C1S gene.
C1s cleaves C4 and C2, which eventually leads to the production of the classical pathway C3-convertase.
See also
- C1q - another part of the C1 complex
- C1r - another part of the C1 complex
- MASP-2 - a protein similar to C1s, part of the lectin pathway
References
Further reading
External links
- Complement+C1s at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Human C1S genome location and C1S gene details page in the UCSC Genome Browser.