Disco interacting protein 2 homolog C

DIP2C
Identifiers
Aliases	DIP2C, KIAA0934, disco interacting protein 2 homolog C
External IDs	OMIM: 611380; MGI: 1920179; GeneCards: DIP2C
Gene location (Human)
Chr.	Chromosome 10 (human)
End	689,668 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	9,718,964 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; middle frontal gyrus; ; paraflocculus of cerebellum; ; tibia; ; middle temporal gyrus; ; saphenous vein; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; endothelial cell; ; Region I of hippocampus proper;
	Top expressed in
	lateral septal nucleus; ; facial motor nucleus; ; pontine nuclei; ; olfactory tubercle; ; amygdala; ; nucleus accumbens; ; superior cervical ganglion; ; substantia nigra; ; medial vestibular nucleus; ; anterior horn of spinal cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	catalytic activity; molecular function;
Cellular component	cellular component;
Biological process	metabolism; biological process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	22982
	208440
	ENSG00000151240
	ENSMUSG00000048264
	Q9Y2E4
	n/a
	NM_014974
	NM_001081426; NM_172459
	NP_055789
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Disco interacting protein 2 homolog C is a protein that in humans is encoded by the DIP2C gene.

Function

This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008].

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000151240 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000048264 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Disco interacting protein 2 homolog C". Retrieved 2018-07-26.

Mukhopadhyay M, Pelka P, DeSousa D, Kablar B, Schindler A, Rudnicki MA, Campos AR (June 2002). "Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog". Gene. 293 (1–2): 59–65. doi:10.1016/s0378-1119(02)00694-7. PMID 12137943.
Oguri M, Kato K, Yokoi K, Yoshida T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y (January 2010). "Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals". Am. J. Hypertens. 23 (1): 70–7. doi:10.1038/ajh.2009.190. PMID 19851296.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y (April 2010). "Association of genetic variants with hemorrhagic stroke in Japanese individuals". Int. J. Mol. Med. 25 (4): 649–56. doi:10.3892/ijmm_00000388. PMID 20198315.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
Li WD, Jiao H, Wang K, Zhang CK, Glessner JT, Grant SF, Zhao H, Hakonarson H, Arlen Price R (September 2013). "A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls". Obesity (Silver Spring). 21 (9): E490–4. doi:10.1002/oby.20303. PMC 3762924. PMID 23703922.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000151240 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000048264 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Disco interacting protein 2 homolog C". Retrieved 2018-07-26.

Disco interacting protein 2 homolog C

Function

References

Further reading