| Discadenine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.24 | ||||||||
| CAS no. | 74082-52-3 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Discadenine synthase (EC 2.5.1.24) is an enzyme characterised from Dictyostelium discoideum that catalyzes a chemical reaction which converts N6-isopentenyladenine to discadenine. It transfers the 3-amino-3-carboxypropyl group from the coenzyme, S-adenosyl methionine, giving 5'-methylthioadenosine as a byproduct.
The product discadenine inhibits spore germination in this soil-dwelling amoeba.
This enzyme is a transferase, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase. Other names in common use include discadenine synthetase, S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine, and 3-(3-amino-3-carboxypropyl)-transferase.
