HCE may refer to:
- HCE (car), a British cyclecar
- Humboldt Current ecosystem
- Choriolysin H, an enzyme
- Harvey Comics Entertainment
- Hawaii Creole English language
- Hexachloroethane
- Hierarchical Cluster Engine Project
- Host card emulation
- RNGTT, a protein
- Humphrey Chimpden Earwicker, a character in James Joyce's novel Finnegans Wake
- Halo: Combat Evolved
This disambiguation page lists articles associated with the title HCE.
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