OSF

OSF may refer to:

• Open Science Framework, a cloud-based management for open access science
• Open Semantic Framework, an integrated software stack using semantic technologies for knowledge management
• OSF/1, a Unix-like operating system developed by the Open Software Foundation
• Opera Show Format, an XHTML-based slideshow format

• Ógra Shinn Féin, the youth wing of the Sinn Féin political party
• Open Software Foundation, a not-for-profit organization that merged with X/Open and then became The Open Group
• Open Society Foundations, a grantmaking body established by George Soros
• OpenStack Foundation, a non-profit corporate entity to promote OpenStack software and its community
• Operational Support Facility, of the Federal Aviation Administration
• Oregon Shakespeare Festival, a repertory theatre in Ashland, Oregon, US
• Oxford Scientific Films, a British producer of natural history and documentary programmes
• The Old Spaghetti Factory, a restaurant chain
• Independent Senate Fraction (Onafhankelijke Senaatsfractie), a political group of the Netherlands
• Order of Saint Francis, a 21st-century American Franciscan religious order
• Oklahoma Office of State Finance, an agency of the Government of Oklahoma, US
• OSF Global Services, a cloud technology company
• OSF Healthcare, a non-profit healthcare organization in Illinois and Michigan, US