PFDN5

Prefoldin subunit 5 is a protein that in humans is encoded by the PFDN5 gene.

This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.

Interactions

PFDN5 has been shown to interact with Myc.

References

Further reading


Uses material from the Wikipedia article PFDN5, released under the CC BY-SA 4.0 license.