Salt-and-pepper chromatin

In pathology, salt-and-pepper chromatin, also known as salt-and-pepper nuclei or stippled chromatin, refers to cell nuclei that demonstrate granular chromatin when observed via light microscopy.

Salt-and-pepper chromatin is typically seen in endocrine tumours such as medullary thyroid carcinoma, neuroendocrine tumours and pheochromocytoma.

Additional images

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  Neuroendocrine tumour of the lung with salt-and-pepper chromatin. H&E stain.
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  Neuroendocrine tumour of the small intestine with salt-and-pepper chromatin. H&E stain.
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  A pheochromocytoma showing finely granular chromatin. H&E stain.
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  Salt-and-pepper chromatin (pheochromocytoma). H&E stain.

References

External links

• Salt-and-pepper chromatin - nature.com.
• Salt-and-pepper nucleus - upmc.edu.

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