Winged-helix transcription factors

Consisting of about 110 amino acids, the domain in winged-helix transcription factors (see Regulation of gene expression) has four helices and a two-strand beta-sheet.

These proteins are classified into 19 families called FoxA-FoxS.

Mutations in FoxP proteins are implicated in human autoimmune diseases.

• FOX proteins

• Winged-Helix+Transcription+Factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)