Aducina gama

ADD3
Identificadores
Nomes alternativos	ADD3
IDs externos	OMIM: 601568 HomoloGene: 40893 GeneCards: ADD3
Ontologia genética
Função molecular	• structural molecule activity; • actin binding; • structural constituent of cytoskeleton; • calmodulin binding; • spectrin binding; • actin filament binding;
Componente celular	• condensed nuclear chromosome; • citosol; • membrana plasmática; • cell cortex; • citoesqueleto; • membrane; • brush border; • cariolinfa; • cell-cell junction; • citoplasma; • GO:0097483, GO:0097481 postsynaptic density; • plasma membrane raft;
Processo biológico	• transmembrane transport; • cytoskeleton organization; • barbed-end actin filament capping; • actin filament bundle assembly;
	Sources:Amigo / QuickGO
Padrão de expressão RNA
	; ; ; ;
	Mais dados de referência de expressão
Ortólogos
	120
	n/a
	ENSG00000148700
	n/a
	Q9UEY8
	n/a
NM_001121; NM_016824; NM_019903; NM_001320591; NM_001320592;
	NM_001320593; NM_001320594
	n/a
NP_001112; NP_001307520; NP_001307521; NP_001307522; NP_001307523;
	NP_058432; NP_063968
	n/a
	Wikidata
Ver/Editar Humano

Aducina gama é uma proteína que em humanos é codificada pelo gene ADD3.

Referências

↑ «Human PubMed Reference:»
↑ Katagiri T, Ozaki K, Fujiwara T, Shimizu F, Kawai A, Okuno S, Suzuki M, Nakamura Y, Takahashi E, Hirai Y (dezembro de 1996). «Cloning, expression and chromosome mapping of adducin-like 70 (ADDL), a human cDNA highly homologous to human erythrocyte adducin». Cytogenet Cell Genet. 74 (1–2): 90–5. PMID 8893809. doi:10.1159/000134389
↑ «Entrez Gene: ADD3 adducin 3 (gamma)»

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Leitura adicional

Kaiser HW, O'Keefe E, Bennett V (1989). «Adducin: Ca++-dependent association with sites of cell-cell contact». J. Cell Biol. 109 (2): 557–69. PMC 2115715. PMID 2503523. doi:10.1083/jcb.109.2.557
Maruyama K, Sugano S (1994). «Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides». Gene. 138 (1–2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). «Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library». Gene. 200 (1–2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3
Gilligan DM, Lozovatsky L, Gwynn B, et al. (1999). «Targeted disruption of the β adducin gene (Add2) causes red blood cell spherocytosis in mice». Proc. Natl. Acad. Sci. U.S.A. 96 (19): 10717–22. PMC 17949. PMID 10485892. doi:10.1073/pnas.96.19.10717
Citterio L, Azzani T, Duga S, Bianchi G (2000). «Genomic organization of the human gamma adducin gene». Biochem. Biophys. Res. Commun. 266 (1): 110–4. PMID 10581174. doi:10.1006/bbrc.1999.1769
Gilligan DM, Sarid R, Weese J (2002). «Adducin in platelets: activation-induced phosphorylation by PKC and proteolysis by calpain». Blood. 99 (7): 2418–26. PMID 11895774. doi:10.1182/blood.V99.7.2418
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). «Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences». Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241. PMID 12477932. doi:10.1073/pnas.242603899
Gerhard DS, Wagner L, Feingold EA, et al. (2004). «The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)». Genome Res. 14 (10B): 2121–7. PMC 528928. PMID 15489334. doi:10.1101/gr.2596504
Gocke CB, Yu H, Kang J (2005). «Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates». J. Biol. Chem. 280 (6): 5004–12. PMID 15561718. doi:10.1074/jbc.M411718200
Lanzani C, Citterio L, Jankaricova M, et al. (2005). «Role of the adducin family genes in human essential hypertension». J. Hypertens. 23 (3): 543–9. PMID 15716695. doi:10.1097/01.hjh.0000160210.48479.78
Yenerel MN, Sundell IB, Weese J, et al. (2005). «Expression of adducin genes during erythropoiesis: a novel erythroid promoter for ADD2». Exp. Hematol. 33 (7): 758–66. PMID 15963851. doi:10.1016/j.exphem.2005.03.015
Olsen JV, Blagoev B, Gnad F, et al. (2006). «Global, in vivo, and site-specific phosphorylation dynamics in signaling networks». Cell. 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026

[1] «Human PubMed Reference:»

[pmid8893809-2] Katagiri T, Ozaki K, Fujiwara T, Shimizu F, Kawai A, Okuno S, Suzuki M, Nakamura Y, Takahashi E, Hirai Y (dezembro de 1996). «Cloning, expression and chromosome mapping of adducin-like 70 (ADDL), a human cDNA highly homologous to human erythrocyte adducin». Cytogenet Cell Genet. 74 (1–2): 90–5. PMID 8893809. doi:10.1159/000134389

[entrez-3] «Entrez Gene: ADD3 adducin 3 (gamma)»

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Tópicos relacionados	Projeto Genoma Humano