GRB2

Growth factor receptor-bound protein 2
Indicadores
SímboloGrb2
Símbolos alt.ASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084
Entrez2885
OMIM108355
RefSeqNP_002077
UniProtP62993
Outros dados
LocusCr. 17

Growth factor receptor-bound protein 2 também conhecido como Grb2 é uma proteína adptadora envolvida na transdução de sinal/sinalização celular. Nos humanos a proteína GRB2 é codificada pelo gene GRB2.

Interações

Grb2 mostrou interação com Arachidonate 5-lipoxygenase, Lymphocyte cytosolic protein 2, GAB2, B-cell linker, Abl gene, CD28, FRS2, Mitogen-activated protein kinase 9, CD22, NEU3, ETV6, MAP2, Dock180, PIK3R1, SH2B1, CRK, GAB1, MST1R, DNM1, Huntingtin, Src, Beta-2 adrenergic receptor, VAV2, ADAM15, RAPGEF1, VAV1, HER2/neu, Epidermal growth factor receptor, PDGFRB, PTK2, Erythropoietin receptor, Linker of activated T cells, Dystroglycan, SH3KBP1, Granulocyte colony-stimulating factor receptor, DCTN1, CDKN1B, Colony stimulating factor 1 receptor, EPH receptor A2, KHDRBS1, RET proto-oncogene, PLCG1, TrkA, PRKAR1A, Janus kinase 2, MUC1, CD117, Fas ligand, Janus kinase 1, VAV3, BCAR1, PTPN1, INPP5D, ITK, SHC1, PTPN12, C-Met, PTPN11, Glycoprotein 130, PTPN6, Syk, MAP4K1, Wiskott-Aldrich syndrome protein, NCKIPSD, PTPRA, BCR gene, CBLB, Cbl gene, SOS1, IRS1, TNK2, MED28, MAP3K1 e HNRNPC.

Referências

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