| Cosimo II | |
|---|---|
 Cosimo II after Justus Sustermans | |
| Grand Duke of Tuscany | |
| Reign | 17 February 1609 – 28 February 1621 |
| Predecessor | Ferdinando I |
| Successor | Ferdinando II |
| Born | 12 May 1590 Palazzo Pitti, Florence, Tuscany |
| Died | February 28, 1621 (aged 30) Palazzo Pitti, Florence, Tuscany |
| Consort | Maria Maddalena of Austria |
| Issue | Ferdinando II, Grand Duke of Tuscany Cardinal Gian Carlo Margherita, Duchess of Parma Prince Mattias, Governor of Siena Prince Francesco Anna, Archduchess of Austria Cardinal Leopoldo |
| House | House of Medici |
| Father | Grand Duke Ferdinando I of Tuscany |
| Mother | Christine of Lorraine |
| Religion | Roman Catholicism |
Cosimo II de' Medici (12 May 1590 – 28 February 1621) was Grand Duke of Tuscany from 1609 until 1621. He was the elder son of Ferdinando I de' Medici, Grand Duke of Tuscany and Christine of Lorraine. He married Maria Magdalena of Austria and had eight children. Galileo Galilei was his childhood tutor.
For the most of his eleven-year reign, he delegated the administration of Tuscany to his ministers. He is best remembered as the patron of Galileo Galilei, his childhood tutor.
He died of tuberculosis in 1621.