Endrin

Endrin
Names
IUPAC name
(1R,2S,3R,6S,7R,8S,9S,11R)-3,4,5,6,13,13-Hexachloro-10-oxapentacyclo[6.3.1.13,6.02,7.09,11]tridec-4-ene
Other names
Mendrin, Compound 269, (1aR,2S,2aS,3S,6R,6aR,7R,7aS)-3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxirene, 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4-endo,endo-5,8-dimethanonaphthalene
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.705
EC Number
  • 200-775-7
KEGG
RTECS number
  • IO1575000
UNII
UN number 2761
  • C1C2C3C(C1C4C2O4)C5(C(=C(C3(C5(Cl)Cl)Cl)Cl)Cl)Cl
Properties
C12H8Cl6O
Molar mass 380.907 g/mol
Appearance Colorless to tan crystalline solid
Density 1.77 g/cm3
Melting point 200 °C (392 °F; 473 K) (decomposes)
0.23 mg/L
Vapor pressure 2.6 x 10-5 Pa
Hazards
GHS labelling:
GHS06: ToxicGHS08: Health hazardGHS09: Environmental hazard
Danger
H301, H310, H351, H372, H410
P201, P202, P260, P262, P264, P270, P273, P280, P281, P301+P310, P302+P350, P308+P313, P310, P314, P321, P322, P330, P361, P363, P391, P405, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
2
0
0
Flash point noncombustible
Lethal dose or concentration (LD, LC):
3 mg/kg (oral, monkey)
16 mg/kg (oral, guinea pig)
10 mg/kg (oral, hamster)
3 mg/kg (oral, rat)
7 mg/kg (oral, rabbit)
1.4 mg/kg (oral, mouse)
5 mg/kg (cat, oral)
NIOSH (US health exposure limits):
PEL (Permissible)
 TWA 0.1 mg/m3 [skin]
REL (Recommended)
 TWA 0.1 mg/m3 [skin]
IDLH (Immediate danger)
 2 mg/m3
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Endrin is an insecticide that was commonplace among cotton growers and for the treament of cereals. It was also used to kill rodents. It is a neurotoxin. It is a stereoisomer of Dieldrin. In the soil, it can take up to twelve years to decay. It is one of the twelve substances listed in the Stockholm Convention on Persistent Organic Pollutants, and its production, trade and use is banned since 2004.

References

  1. 1 2 "Endrin". Deutsche Gesellschaft für Technische Zusammenarbeit. Retrieved 13 March 2015.
  2. ↑ "Endrin (PDS)". IPCS. Archived from the original on 2 July 2014. Retrieved 13 March 2015.
  3. 1 2 3 4 NIOSH Pocket Guide to Chemical Hazards. "#0252". National Institute for Occupational Safety and Health (NIOSH).
  4. 1 2 "Endrin". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH). 4 December 2014. Retrieved 19 March 2015.