A casta painting of a European man and an Indigenous American woman with a Mestizo child | |
| Regions with significant populations | |
|---|---|
| Latin America, United States, Spain, Philippines, Micronesia | |
| Languages | |
| Religion | |
| Predominantly Roman Catholic; religious minorities include Protestants and syncretism with Native American beliefs, animism, or Anito exist | |
| Related ethnic groups | |
| Spaniards Indigenous peoples of the Americas Negritos Chinese people Métis |

Mestizo (meh-STEE-tzo), is a Spanish term for a mixed person who is of Native American and European ancestry. It is most often used with mixed race people.
Mestizos have existed since men from Spain controlled much of what is now Latin America. "Mestizo" is the masculine form; "Mestiza" the feminine. Mestizos form the largest part of the population in some Latin American nations. A large minority of Mestizos makes up most of the population in Mexico, the Spanish-speaking nation with the largest population in the world.
During the colonial era, many Native Americans converted to Roman Catholicism and began using Spanish instead of their traditional language. That was because of the racial hierarchy that existed in the Spanish colonies, which gave Spaniards a higher social class than Native Americans and free or enslaved West Africans. That has made many Native Americans gain a better social status by calling themselves "Mestizos" instead of "Indios."
Indo-Mestizo (also known as Cholo, is a Spanish term for a person who has around three-fourths Native American and one-fourth Spanish ancestry, It is a derogatory term used by the Spanish caste system for racial segregation and discrimination against original Native people.
It is a racial slur used that discriminates mostly against original Native people in eastern and southern Mexico, much of Northern Central America, the Pacific side of Ecuador, Peru, Chile, Colombia, and Bolivia.
Indo-Mestizos usually have more Native American traits but may have either a light pigmentation with completely Native American features or a dark pigmentation with some obvious Spanish features.
Famous Mestizos or Mestizas are Maya Zapata, George Lopez, and Danny Trejo. They are called so because of their appearance, not because of their known genetic background.
Mestizo Americans are people in the United States whose racial and/or ethnic identity is Mestizo, a mixed ancestry of European and Native American from Latin America.