Toxicofera

Toxicofera
	Venomous snakes, such as the rattlesnake shown above, are the most well-known venomous squamates.
Scientific classification
Kingdom:	Animalia
Phylum:	Chordata
Subphylum:	Vertebrata
Class:	Sauropsida
Subclass:	Diapsida
Infraclass:	Lepidosauromorpha
Superorder:	Lepidosauria
Order:	Squamata
(unranked):	Toxicofera

Toxicofera (Greek or Latin for "those who carry toxins"), is a hypothetical clade of living Squamata (lizards and snakes). It includes about 4600 living species. This is all venomous reptile species, plus related non-venomous species.

The clade was identified when research showed that the evolution of venom was very ancient, and that it might have occurred only once.

Cladistics

The Toxicofera combines the following groups from traditional classification:

Suborder Serpentes (snakes)
Suborder Iguania (iguanas, agamid lizards, chameleons, etc.)
Infraorder Anguimorpha, consisting of:
- Family Varanidae (monitor lizards)
- Family Anguidae (alligator lizards, glass lizards, etc.)
- Family Helodermatidae (Gila monster and Mexican beaded lizard)

References

1 2 Fry, Bryan G.; Vidal, Nicolas; Norman, Janette A.; et al. (February 2006). "Early evolution of the venom system in lizards and snakes". Nature. 439 (7076): 584–588. Bibcode:2006Natur.439..584F. doi:10.1038/nature04328. ISSN 0028-0836. PMID 16292255. S2CID 4386245. Archived from the original on 2022-04-11. Retrieved 2022-04-25.
↑ Fry, B. G.; Wuster, W.; Kini, R. M.; Brusic, V.; Khan, A.; Venkataraman, D.; Rooney, A. P. (2003-07-01). "Molecular Evolution and Phylogeny of Elapid Snake Venom Three-Finger Toxins". Journal of Molecular Evolution. 57 (1): 110–129. Bibcode:2003JMolE..57..110F. doi:10.1007/s00239-003-2461-2. ISSN 0022-2844. PMID 12962311. S2CID 12358977.
↑ Fry, B. et al. 2003 (2003). "Isolation of a neurotoxin (α-colubritoxin) from a nonvenomous colubrid: evidence for early origin of venom in snakes". Journal of Molecular Evolution. 57 (4): 446–452. Bibcode:2003JMolE..57..446F. doi:10.1007/s00239-003-2497-3. PMID 14708577. S2CID 21055188.{{cite journal}}: CS1 maint: numeric names: authors list (link)
↑ Fry, B. G. (2004-01-22). "Assembling an Arsenal: Origin and Evolution of the Snake Venom Proteome Inferred from Phylogenetic Analysis of Toxin Sequences". Molecular Biology and Evolution. 21 (5): 870–883. doi:10.1093/molbev/msh091. ISSN 0737-4038. PMID 15014162. Archived from the original on 2022-06-17. Retrieved 2022-04-25.

[Fry2006-1] 1 2 Fry, Bryan G.; Vidal, Nicolas; Norman, Janette A.; et al. (February 2006). "Early evolution of the venom system in lizards and snakes". Nature. 439 (7076): 584–588. Bibcode:2006Natur.439..584F. doi:10.1038/nature04328. ISSN 0028-0836. PMID 16292255. S2CID 4386245. Archived from the original on 2022-04-11. Retrieved 2022-04-25.

[Fry2003-2] Fry, B. G.; Wuster, W.; Kini, R. M.; Brusic, V.; Khan, A.; Venkataraman, D.; Rooney, A. P. (2003-07-01). "Molecular Evolution and Phylogeny of Elapid Snake Venom Three-Finger Toxins". Journal of Molecular Evolution. 57 (1): 110–129. Bibcode:2003JMolE..57..110F. doi:10.1007/s00239-003-2461-2. ISSN 0022-2844. PMID 12962311. S2CID 12358977.

[Fry2003-ratsnake-3] Fry, B. et al. 2003 (2003). "Isolation of a neurotoxin (α-colubritoxin) from a nonvenomous colubrid: evidence for early origin of venom in snakes". Journal of Molecular Evolution. 57 (4): 446–452. Bibcode:2003JMolE..57..446F. doi:10.1007/s00239-003-2497-3. PMID 14708577. S2CID 21055188.{{cite journal}}: CS1 maint: numeric names: authors list (link)

[Fry2004-4] Fry, B. G. (2004-01-22). "Assembling an Arsenal: Origin and Evolution of the Snake Venom Proteome Inferred from Phylogenetic Analysis of Toxin Sequences". Molecular Biology and Evolution. 21 (5): 870–883. doi:10.1093/molbev/msh091. ISSN 0737-4038. PMID 15014162. Archived from the original on 2022-06-17. Retrieved 2022-04-25.