5-HT1F-Rezeptor

5-HT1F-Rezeptor
5-HT1F-Rezeptor
Bezeichner
Externe IDs
Orthologe
Mensch Hausmaus
Entrez 3355 15557
Ensembl ENSG00000179097 ENSMUSG00000050783
UniProt P30939 Q02284
Refseq (mRNA) NM_000866 NM_008310
Refseq (Protein) NP_000857 NP_032336
Genlocus Chr 3: 87.79 – 87.99 Mb Chr 16: 64.92 – 65.11 Mb
PubMed-Suche 3355 15557

Der 5-HT1F-Rezeptor, auch bekannt als HTR1F, ist ein 5-HT-Rezeptorprotein und bezeichnet auch das menschliche Gen, das dafür kodiert.

Agonisten

Einzelnachweise

  1. ↑ HTR1F 5-hydroxytryptamine receptor 1F (Homo sapiens (human)) - Gene - NCBI. Abgerufen am 5. Oktober 2021 (englisch).
  2. ↑ N. Adham, H. T. Kao, L. E. Schecter, J. Bard, M. Olsen: Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase. In: Proceedings of the National Academy of Sciences. Band 90, Nr. 2, 15. Januar 1993, ISSN 0027-8424, S. 408–412, doi:10.1073/pnas.90.2.408, PMID 8380639.
  3. ↑ T. W. Lovenberg, M. G. Erlander, B. M. Baron, M. Racke, A. L. Slone: Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes. In: Proceedings of the National Academy of Sciences of the United States of America. Band 90, Nr. 6, 15. März 1993, ISSN 0027-8424, S. 2184–2188, doi:10.1073/pnas.90.6.2184, PMID 8384716.
  4. ↑ J. Erdmann, D. Shimron-Abarbanell, V. Shridhar, D. I. Smith, P. Propping: Assignment of the human serotonin 1F receptor gene (HTR1F) to the short arm of chromosome 3 (3p13-p14.1). In: Molecular Membrane Biology. Band 14, Nr. 3, Juli 1997, ISSN 0968-7688, S. 133–135, doi:10.3109/09687689709048173, PMID 9394293.
  5. ↑ A. Maassen VanDenBrink, M. N. Vergouwe, R. A. Ophoff, S. L. Naylor, H. G. Dauwerse: Chromosomal localization of the 5-HT1F receptor gene: no evidence for involvement in response to sumatriptan in migraine patients. In: American Journal of Medical Genetics. Band 77, Nr. 5, 5. Juni 1998, ISSN 0148-7299, S. 415–420, PMID 9632173.
  6. ↑ Michael T. Klein, Małgorzata Dukat, Richard A. Glennon, Milt Teitler: Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships. In: The Journal of Pharmacology and Experimental Therapeutics. Band 337, Nr. 3, Juni 2011, ISSN 1521-0103, S. 860–867, doi:10.1124/jpet.111.179606, PMID 21422162, PMC 3101003 (freier Volltext).
  7. ↑ David B. Wainscott, Joseph H. Krushinski, James E. Audia, John M. Schaus, John M. Zgombick: [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. In: Naunyn-Schmiedeberg's Archives of Pharmacology. Band 371, Nr. 3, März 2005, ISSN 0028-1298, S. 169–177, doi:10.1007/s00210-005-1035-9, PMID 15900510.
  8. ↑ Deyi Zhang, Dan Kohlman, Joseph Krushinski, Sidney Liang, Bai-Ping Ying: Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists. In: Bioorganic & Medicinal Chemistry Letters. Band 14, Nr. 24, 20. Dezember 2004, ISSN 0960-894X, S. 6011–6016, doi:10.1016/j.bmcl.2004.09.079, PMID 15546719.