AGPAT5

AGPAT5
Identifiers
Aliases	AGPAT5, 1LPAATE, 1-acylglycerol-3-phosphate O-acyltransferase 5
External IDs	OMIM: 614796; MGI: 1196345; GeneCards: AGPAT5
Enzyme activity
Gene location (Human)
Chr.	Chromosome 8 (human)
End	6,761,503 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	18,941,377 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; ventricular zone; ; ganglionic eminence; ; left testis; ; right testis; ; endometrium; ; C1 segment; ; Achilles tendon; ; caudate nucleus; ; islet of Langerhans;
	Top expressed in
	triceps brachii muscle; ; sternocleidomastoid muscle; ; temporal muscle; ; digastric muscle; ; skin of external ear; ; seminal vesicula; ; endothelial cell of lymphatic vessel; ; pineal gland; ; umbilical cord; ; decidua;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein binding; acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity;
Cellular component	integral component of membrane; nuclear envelope; membrane; endoplasmic reticulum membrane; mitochondrial outer membrane; mitochondrion; endoplasmic reticulum; nucleus;
Biological process	phosphatidic acid biosynthetic process; CDP-diacylglycerol biosynthetic process; lipid metabolism; hematopoietic progenitor cell differentiation; phospholipid biosynthetic process; metabolism; acylglycerol metabolic process; phospholipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	55326
	52123
	ENSG00000155189; ENSG00000284980
	ENSMUSG00000031467
	Q9NUQ2
	Q9D1E8
	NM_018361
	NM_026792
	NP_060831
	NP_081068
	Wikidata
View/Edit Human	View/Edit Mouse

1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon is an enzyme that is encoded by the AGPAT5 gene in humans.

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis.