AGR3

AGR3
Identifiers
Aliases	AGR3, AG3, BCMP11, HAG3, PDIA18, hAG-3, AG-3, anterior gradient 3, protein disulphide isomerase family member
External IDs	OMIM: 609482; MGI: 2685734; GeneCards: AGR3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3PH9
Gene location (Human)
Chr.	Chromosome 7 (human)
End	16,881,987 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	35,999,735 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; mucosa of ileum; ; mucosa of sigmoid colon; ; right uterine tube; ; rectum; ; jejunal mucosa; ; mucosa of transverse colon; ; pancreatic epithelial cell; ; duodenum; ; trachea;
	Top expressed in
	saccule; ; vestibular sensory epithelium; ; utricle; ; olfactory epithelium; ; primary oocyte; ; zygote; ; secondary oocyte; ; right lung lobe; ; trachea; ; cochlea;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; dystroglycan binding;
Cellular component	endoplasmic reticulum; cellular component; intracellular membrane-bounded organelle;
Biological process	cell differentiation; negative regulation of cell death; biological process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	155465
	403205
	ENSG00000173467
	ENSMUSG00000036231
	Q8TD06
	Q8R3W7
	NM_176813
	NM_207531
	NP_789783
	NP_997414
	Wikidata
View/Edit Human	View/Edit Mouse

Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000173467 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036231 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Fletcher GC, Patel S, Tyson K, Adam PJ, Schenker M, Loader JA, Daviet L, Legrain P, Parekh R, Harris AL, Terrett JA (Feb 2003). "hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan". British Journal of Cancer. 88 (4): 579–85. doi:10.1038/sj.bjc.6600740. PMC 2377166. PMID 12592373.
↑ Adam PJ, Boyd R, Tyson KL, Fletcher GC, Stamps A, Hudson L, Poyser HR, Redpath N, Griffiths M, Steers G, Harris AL, Patel S, Berry J, Loader JA, Townsend RR, Daviet L, Legrain P, Parekh R, Terrett JA (Feb 2003). "Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer". The Journal of Biological Chemistry. 278 (8): 6482–9. doi:10.1074/jbc.M210184200. PMID 12477722.
↑ "Entrez Gene: AGR3 anterior gradient homolog 3 (Xenopus laevis)".

Human AGR3 genome location and AGR3 gene details page in the UCSC Genome Browser.

Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Zhang Z, Henzel WJ (Oct 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Science. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
Persson S, Rosenquist M, Knoblach B, Khosravi-Far R, Sommarin M, Michalak M (Sep 2005). "Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family". Molecular Phylogenetics and Evolution. 36 (3): 734–40. doi:10.1016/j.ympev.2005.04.002. PMID 15935701.

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