AK3

AK3
Identifiers
Aliases	AK3, AK3L1, AK6, AKL3L, AKL3L1, FIX, adenylate kinase 3
External IDs	OMIM: 609290; MGI: 1860835; GeneCards: AK3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZD8
Enzyme activity
Gene location (Human)
Chr.	Chromosome 9 (human)
End	4,742,043 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	29,025,361 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; myocardium of left ventricle; ; skin of arm; ; deltoid muscle; ; tibialis anterior muscle; ; mucosa of ileum; ; jejunal mucosa; ; vastus lateralis muscle; ; biceps brachii; ; right ventricle;
	Top expressed in
	epithelium of stomach; ; parotid gland; ; pyloric antrum; ; submandibular gland; ; seminal vesicula; ; left colon; ; brown adipose tissue; ; right kidney; ; retinal pigment epithelium; ; mucous cell of stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; nucleobase-containing compound kinase activity; GTP binding; ATP binding; protein binding; phosphotransferase activity, phosphate group as acceptor; kinase activity; nucleoside triphosphate adenylate kinase activity; adenylate kinase activity;
Cellular component	mitochondrial matrix; mitochondrion;
Biological process	UTP metabolic process; blood coagulation; nucleobase-containing compound metabolic process; phosphorylation; AMP metabolic process; GTP metabolic process; ITP metabolic process; nucleoside monophosphate phosphorylation; ADP biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	50808
	56248
	ENSG00000147853
	ENSMUSG00000024782
	Q9UIJ7
	Q9WTP7
NM_016282; NM_001199852; NM_001199853; NM_001199854; NM_001199855;
	NM_001199856
	NM_021299; NM_001365071
	NP_001186781; NP_001186782; NP_001186784; NP_001186785; NP_057366
	NP_067274; NP_001352000
	Wikidata
View/Edit Human	View/Edit Mouse

Adenylate kinase 3 is a protein that in humans is encoded by the AK3 gene.

Function

The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000147853 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024782 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Adenylate kinase 3". Retrieved 2017-05-19.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human GTP:AMP phosphotransferase AK3, mitochondrial (AK3)

AK3

Function

References

External links

Further reading