ALG11

ALG11
Identifiers
Aliases	ALG11, CDG1P, GT8, alpha-1,2-mannosyltransferase, ALG11 alpha-1,2-mannosyltransferase
External IDs	OMIM: 613666; MGI: 2142632; GeneCards: ALG11
Enzyme activity
Gene location (Human)
Chr.	Chromosome 13 (human)
End	52,079,232 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	22,561,643 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; Achilles tendon; ; endometrium; ; epithelium of colon; ; gonad; ; bone marrow cell; ; placenta; ; tonsil; ; corpus callosum; ; testicle;
	Top expressed in
	spermatocyte; ; genital tubercle; ; hand; ; tail of embryo; ; supraoptic nucleus; ; seminal vesicula; ; superior cervical ganglion; ; medullary collecting duct; ; trigeminal ganglion; ; substantia nigra;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; glycosyltransferase activity; GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity;
Cellular component	integral component of membrane; endoplasmic reticulum; membrane; endoplasmic reticulum membrane;
Biological process	mannosylation; oligosaccharide-lipid intermediate biosynthetic process; protein N-linked glycosylation;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	440138
	207958
	ENSG00000253710
	ENSMUSG00000063362
	Q2TAA5
	Q3TZM9
	NM_001004127
	NM_001243161; NM_183142
	NP_001004127
	NP_001230090; NP_898965
	Wikidata
View/Edit Human	View/Edit Mouse

Asparagine-linked glycosylation protein 11 is an enzyme encoded by the ALG11 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000253710 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000063362 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: asparagine-linked glycosylation 11".
↑ Cipollo JF, Trimble RB, Chi JH, Yan Q, Dean N (June 2001). "The yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum". The Journal of Biological Chemistry. 276 (24): 21828–21840. doi:10.1074/jbc.m010896200. PMID 11278778.
↑ Gao XD, Nishikawa A, Dean N (June 2004). "Physical interactions between the Alg1, Alg2, and Alg11 mannosyltransferases of the endoplasmic reticulum". Glycobiology. 14 (6): 559–570. doi:10.1093/glycob/cwh072. PMID 15044395.

Human ALG11 genome location and ALG11 gene details page in the UCSC Genome Browser.

This article on a gene on human chromosome 13 is a stub. You can help Wikipedia by adding missing information.