ALKAL1

ALKAL1
Identifiers
Aliases	ALKAL1, UNQ9433, FAM150A, family with sequence similarity 150 member A, ALK and LTK ligand 1, AUGB, AUGA
External IDs	MGI: 3645495; GeneCards: ALKAL1
Gene location (Human) Chr. Chromosome 8 (human) Band 8q11.23 Start 52,534,037 bp End 52,565,430 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 A1 Start 6,429,442 bp End 6,464,955 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad gallbladder left lobe of thyroid gland right lobe of thyroid gland duodenum urinary bladder minor salivary glands right lung olfactory zone of nasal mucosa Top expressed in embryo embryo lung olfactory bulb stomach colon More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding receptor signaling protein tyrosine kinase activator activity receptor tyrosine kinase binding Cellular component extracellular region Biological process positive regulation of protein tyrosine kinase activity positive regulation of ERK1 and ERK2 cascade positive regulation of ERK5 cascade positive regulation of neuron projection development Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 389658 620393 Ensembl ENSG00000196711 ENSMUSG00000087247 UniProt Q6UXT8 J3QPP8 RefSeq (mRNA) NM_207413 NM_001195732 RefSeq (protein) NP_997296 NP_001182661 Location (UCSC) Chr 8: 52.53 – 52.57 Mb Chr 1: 6.43 – 6.46 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

ALKAL1, also known as ALK and LTK ligand 1, is a secreted ligand that in humans is encoded by the ALKAL1 gene. ALKAL1 participates in receptor tyrosine kinase signaling pathways, and supports receptor-mediated signaling initiation.

References

This protein-related article is a stub. You can help Wikipedia by adding missing information.

• v
• t
• e