ANAPC11

ANAPC11
Identifiers
AliasesANAPC11, APC11, Apc11p, HSPC214, anaphase promoting complex subunit 11
External IDsOMIM: 614534; MGI: 1913406; GeneCards: ANAPC11
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

51529

66156

Ensembl

ENSG00000141552

ENSMUSG00000025135

UniProt

Q9NYG5

Q9CPX9

RefSeq (mRNA)

NM_001038230
NM_025389

RefSeq (protein)

NP_001033319
NP_079665

Location (UCSC)Chr 17: 81.89 – 81.9 MbChr 11: 120.49 – 120.5 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Anaphase-promoting complex subunit 11 is an enzyme that in humans is encoded by the ANAPC11 gene.

Interactions

ANAPC11 has been shown to interact with ANAPC2 and CDC27.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000141552 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025135 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM (September 2000). "The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex". Proceedings of the National Academy of Sciences of the United States of America. 97 (16): 8973–8978. Bibcode:2000PNAS...97.8973G. doi:10.1073/pnas.97.16.8973. PMC 16806. PMID 10922056.
  6. ↑ "Entrez Gene: ANAPC11 APC11 anaphase promoting complex subunit 11 homolog (yeast)".
  7. ↑ Tang Z, Li B, Bharadwaj R, Zhu H, Ozkan E, Hakala K, et al. (December 2001). "APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex". Molecular Biology of the Cell. 12 (12): 3839–3851. doi:10.1091/mbc.12.12.3839. PMC 60759. PMID 11739784.
  8. ↑ Ohta T, Michel JJ, Schottelius AJ, Xiong Y (April 1999). "ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity". Molecular Cell. 3 (4): 535–541. doi:10.1016/S1097-2765(00)80482-7. PMID 10230407. S2CID 19371828.
  9. ↑ Vodermaier HC, Gieffers C, Maurer-Stroh S, Eisenhaber F, Peters JM (September 2003). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1". Current Biology. 13 (17): 1459–1468. Bibcode:2003CBio...13.1459V. doi:10.1016/S0960-9822(03)00581-5. PMID 12956947. S2CID 5942532.

Further reading