ANP32B

ANP32B
Identifiers
Aliases	ANP32B, APRIL, PHAPI2, SSP29, acidic nuclear phosphoprotein 32 family member B
External IDs	MGI: 1914878; GeneCards: ANP32B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ELL, 2RR6
Gene location (Human)
Chr.	Chromosome 9 (human)
End	98,015,943 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	46,472,657 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; trabecular bone; ; optic nerve; ; thymus; ; internal globus pallidus; ; corpus epididymis; ; cartilage tissue; ; dorsal motor nucleus of vagus nerve; ; parotid gland; ; caput epididymis;
	Top expressed in
	tail of embryo; ; genital tubercle; ; zygote; ; primary oocyte; ; secondary oocyte; ; bone marrow; ; epiblast; ; yolk sac; ; ventricular zone; ; thymus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	histone binding; protein binding; RNA polymerase binding;
Cellular component	cytoplasm; extracellular exosome; nucleolus; nucleus;
Biological process	positive regulation of protein export from nucleus; negative regulation of cell differentiation; inner ear development; nucleosome assembly; roof of mouth development; vasculature development; activation of cysteine-type endopeptidase activity involved in apoptotic process; ventricular system development; histone exchange;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	10541
	67628
	ENSG00000136938
	ENSMUSG00000028333
	Q92688
	Q9EST5
	NM_006401
	NM_130889
	NP_006392
	NP_570959
	Wikidata
View/Edit Human	View/Edit Mouse

Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) also known as "acidic protein rich in leucines" (APRIL) is a protein that in humans is encoded by the ANP32B gene.

APRIL is also the acronym used for an entirely different protein, TNFSF13, a member of the tumor necrosis factor superfamily whose alternative name, A PRoliferation Inducing Ligand, shares the same acronym as that for ANP32B

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000136938 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028333 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Zhu L, Perlaky L, Henning D, Valdez BC (Jan 1998). "Cloning and characterization of a new silver-stainable protein SSP29, a member of the LRR family". Biochem Mol Biol Int. 42 (5): 927–35. doi:10.1080/15216549700203371. PMID 9285060. S2CID 19749385.
↑ Mencinger M, Panagopoulos I, Contreras JA, Mitelman F, Aman P (Mar 1998). "Expression analysis and chromosomal mapping of a novel human gene, APRIL, encoding an acidic protein rich in leucines". Biochim Biophys Acta. 1395 (2): 176–80. doi:10.1016/S0167-4781(97)00165-6. PMID 9473664.
↑ "Entrez Gene: ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B".

External links

Human ANP32B genome location and ANP32B gene details page in the UCSC Genome Browser.

Matilla A, Radrizzani M (2005). "The Anp32 family of proteins containing leucine-rich repeats". Cerebellum. 4 (1): 7–18. doi:10.1080/14734220410019020. PMID 15895553. S2CID 39153579.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Brennan CM, Gallouzi IE, Steitz JA (2000). "Protein ligands to HuR modulate its interaction with target mRNAs in vivo". J. Cell Biol. 151 (1): 1–14. doi:10.1083/jcb.151.1.1. PMC 2189805. PMID 11018049.
Gallouzi IE, Steitz JA (2001). "Delineation of mRNA export pathways by the use of cell-permeable peptides". Science. 294 (5548): 1895–901. Bibcode:2001Sci...294.1895G. doi:10.1126/science.1064693. PMID 11729309. S2CID 43726887.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Jiang X, Kim HE, Shu H, et al. (2003). "Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway". Science. 299 (5604): 223–6. Bibcode:2003Sci...299..223J. doi:10.1126/science.1076807. PMID 12522243. S2CID 86628810.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Tao WA, Wollscheid B, O'Brien R, et al. (2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nat. Methods. 2 (8): 591–8. doi:10.1038/nmeth776. PMID 16094384. S2CID 20475874.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000136938 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028333 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9285060-5] Zhu L, Perlaky L, Henning D, Valdez BC (Jan 1998). "Cloning and characterization of a new silver-stainable protein SSP29, a member of the LRR family". Biochem Mol Biol Int. 42 (5): 927–35. doi:10.1080/15216549700203371. PMID 9285060. S2CID 19749385.

[pmid9473664-6] Mencinger M, Panagopoulos I, Contreras JA, Mitelman F, Aman P (Mar 1998). "Expression analysis and chromosomal mapping of a novel human gene, APRIL, encoding an acidic protein rich in leucines". Biochim Biophys Acta. 1395 (2): 176–80. doi:10.1016/S0167-4781(97)00165-6. PMID 9473664.

[entrez-7] "Entrez Gene: ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B".

ANP32B

See also

References

External links

Further reading