AP3B2 Protein-coding gene in the species Homo sapiens
AP3B2 Identifiers Aliases AP3B2 External IDs OMIM : 602166 ; MGI : 1100869 ; GeneCards : AP3B2 Gene location (Mouse ) Chr. Chromosome 7 (mouse) Band 7 D3| 7 45.71 cM Start 81,110,147 bp End 81,143,673 bp
RNA expression patternBgee Human Mouse (ortholog)Top expressed in anterior pituitary Brodmann area 10 Brodmann area 9 cingulate gyrus ganglionic eminence amygdala nucleus accumbens hypothalamus Region I of hippocampus proper superior frontal gyrus
Top expressed in dentate gyrus of hippocampal formation granule cell neural layer of retina visual cortex primary visual cortex superior frontal gyrus cerebellar cortex supraoptic nucleus dorsomedial hypothalamic nucleus central gray substance of midbrain facial motor nucleus
More reference expression data
BioGPS
Wikidata
AP-3 complex subunit beta-2 is a protein that in humans is encoded by the AP3B2 gene .
References
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062444 – Ensembl , May 2017↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ Newman LS, McKeever MO, Okano HJ, Darnell RB (Oct 1995). "Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein" . Cell . 82 (5): 773– 83. doi :10.1016/0092-8674(95)90474-3 PMID 7671305 . ↑ Darnell RB, Furneaux HM, Posner JB (Jun 1991). "Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors" . J Neurosci . 11 (5): 1224– 30. doi :10.1523/JNEUROSCI.11-05-01224.1991 . PMC 6575333 PMID 1851215 . ↑ "Entrez Gene: AP3B2 adaptor-related protein complex 3, beta 2 subunit" .
Further reading
Dell'Angelica EC, Ohno H, Ooi CE, et al. (1997). "AP-3: an adaptor-like protein complex with ubiquitous expression" . EMBO J . 16 (5): 917– 28. doi :10.1093/emboj/16.5.917 . PMC 1169692 PMID 9118953 . Dell'Angelica EC, Klumperman J, Stoorvogel W, Bonifacino JS (1998). "Association of the AP-3 adaptor complex with clathrin". Science . 280 (5362): 431– 4. Bibcode :1998Sci...280..431D . doi :10.1126/science.280.5362.431 . PMID 9545220 . Lim DS, Kirsch DG, Canman CE, et al. (1998). "ATM binds to beta-adaptin in cytoplasmic vesicles" . Proc. Natl. Acad. Sci. U.S.A . 95 (17): 10146– 51. Bibcode :1998PNAS...9510146L . doi :10.1073/pnas.95.17.10146 PMC 21476 PMID 9707615 . Faundez VV, Kelly RB (2000). "The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform" . Mol. Biol. Cell . 11 (8): 2591– 604. doi :10.1091/mbc.11.8.2591 . PMC 14942 PMID 10930456 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Dubois T, Zemlickova E, Howell S, Aitken A (2003). "Centaurin-alpha 1 associates in vitro and in vivo with nucleolin". Biochem. Biophys. Res. Commun . 301 (2): 502– 8. doi :10.1016/S0006-291X(02)03010-3 . PMID 12565890 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40– 5. doi :10.1038/ng1285 PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Chen C, Zou X, Ji C, et al. (2007). "Characterization of AP3B2_v2, a novel splice variant of human AP3B2". DNA Seq . 18 (3): 165– 8. doi :10.1080/10425170600842121 . PMID 17453999 . S2CID 725773 .
