Le was born in Hanoi, Vietnam. He lived in several countries across Asia before moving to the United States at the age of 10. Having no understanding of the English language prior to his arrival, he had taught himself by watching cartoons and playing video games. He had an admiration for anime, and often drew Kakashi Hatake from Naruto, initially being aspired to become a manga artist from a young age.
Le moved to Vancouver, Canada alone during his adolescence. He became interested in powerlifting at the age of 14. Wanting to become a personal trainer, he stopped after an injury to his elbow and shoulder.
He did freelance work as both an artist and graphic designer and had even designed a logo for a local restaurant. Additionally, he began a job delivering mail for a local post office.
Le later moved to Florida due to a visa expiration. He briefly attended community college before dropping out to completely shift his focus to voice acting. Unable to afford formal acting classes, he began studying his favorite performances to recreate them. In an interview with Tokyo Weekender, he stated that he would "do 16-18 hour days of just practicing and doing auditions."
He began his voice acting career in 2018, making his Los Angeles debut as the voice of Dahar in The Laws of The Universe: Part 1. He later voice acted in other anime projects as Seijuro Akashi in Kuroko's Basketball and Alexis Deux from Record of Grancrest War. The following year, Le achieved his breakout role when he provided the voice for Zenitsu Agatsuma in Demon Slayer: Kimetsu no Yaiba, which became one of the highest-grossing anime franchises worldwide. In October 2022, he and voice actor Jonah Scott launched the YouTube channel VO to Go, which was supported by Sony Music Entertainment Japan and focused on exploring the voice acting industry.
Le voiced Manjiro "Mikey" Sano in the English dub of Tokyo Revengers. In a 2021 interview with CBR, Le discussed his connection to Mikey's duality, noting that he found aspects of himself in the character and emphasized the importance of compassion for others. In May 2023, he was announced as part of the dubbing cast of Mashle: Magic and Muscles, voicing the character Mash Burnedead. He appeared at an Anime NYC panel in August 2024 alongside anime staff and the hip hop duo Creepy Nuts, dressed in Mash's school robe and holding cream puffs. During the panel, he said that he resonated with his outcast character and noted that portraying him was challenging due to his monotone voice.
In March 2024, Le was announced to be the English voice of Sung Jin-woo, the main character of Solo Leveling. In an interview with CBR, he mentioned that he had taken cues from the original Japanese voice actor Taito Ban, who served as a significant source of inspiration for his performance. At the end of its season 1 run, he responded to fans who threatened him over his delivery of the dialogue "Arise." He jokingly suggested that he might change it to something different while urging fans to ground their expectations. Despite the criticism, he was nominated for Best Voice Artist Performance (English) at the 9th Crunchyroll Anime Awards, ultimately winning the category as Solo Leveling won multiple other awards. At the 4th Astra TV Awards in 2024, when Solo Leveling won the award for Best Anime Series, Le accepted the award on behalf of Aniplex, A-1 Pictures, and Crunchyroll. He reprised his role as Sung Jin-Woo in Solo Leveling: ReAwakening, a theatrical recap and preview of the second season.
In August 2024, it was announced that Le would join the cast of Dandadan, voicing the character Jin "Jiji" Enjoji starting from the 11th episode of the first season. He praised director Alex von David's adaptation of the series and expressed his trust in von David's interpretation of the show and the characters, stating that he has done an excellent job of adapting the material.
On July 23, 2025, Crunchyroll announced that Le would not reprise his role as Kazuya Kinoshita for season 4 of Rent-A-Girlfriend, later revealing that scheduling conflicts and a studio change were the factor and was replaced by Alex Mai.
On June 30, 2026, Le announced his voice director and co-producer debut for the indie video gameCresata as well as providing the voice of the protagonist, Phaedon.
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