Arabidiol synthase

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Arabidiol synthase
Arabidiol synthase
Identifiers
EC no.	4.2.1.124
Databases
BRENDA	enzyme data
ExPASy	NiceZyme view
KEGG	enzyme entry
MetaCyc	metabolic pathway
Rhea	reactions
PDB structures	RCSB PDB PDBe PDBsum
PMC
Search
PMC	articles
PubMed	articles
NCBI	proteins

Arabidiol synthase (EC 4.2.1.124, PEN1 (gene), (S)-squalene-2,3-epoxide hydro-lyase (arabidiol forming)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (arabidiol forming). This enzyme catalyses the following chemical reaction

arabidiol

\rightleftharpoons

(3S)-2,3-epoxy-2,3-dihydrosqualene + H₂O

The reaction occurs in the reverse direction.

References

↑ Xiang T, Shibuya M, Katsube Y, Tsutsumi T, Otsuka M, Zhang H, Masuda K, Ebizuka Y (June 2006). "A new triterpene synthase from Arabidopsis thaliana produces a tricyclic triterpene with two hydroxyl groups". Organic Letters. 8 (13): 2835–8. doi:10.1021/ol060973p. PMID 16774269.

External links

Arabidiol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[1] Xiang T, Shibuya M, Katsube Y, Tsutsumi T, Otsuka M, Zhang H, Masuda K, Ebizuka Y (June 2006). "A new triterpene synthase from Arabidopsis thaliana produces a tricyclic triterpene with two hydroxyl groups". Organic Letters. 8 (13): 2835–8. doi:10.1021/ol060973p. PMID 16774269.

v t e Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase
4.2.2: Acting on polysaccharides	Hyaluronate lyase Pectin lyase
4.2.3: Acting on phosphates	Threonine synthase
4.2.99: Other	Carboxymethyloxysuccinate lyase Hydroperoxide lyase Thebaine synthase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)