BET1 Protein-coding gene in the species Homo sapiens
BET1 homolog is a protein that in humans is encoded by the BET1 gene .
This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex . The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.
References
1 2 3 GRCh38: Ensembl release 89: ENSG00000105829 – Ensembl , May 20171 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032757 – Ensembl , May 2017↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ Zhang T, Wong SH, Tang BL, Xu Y, Peter F, Subramaniam VN, et al. (December 1997). "The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus" . The Journal of Cell Biology . 139 (5): 1157– 1168. doi :10.1083/jcb.139.5.1157 . PMC 2140212 PMID 9382863 . ↑ Waters MG, Pfeffer SR (November 1999). "Membrane tethering in intracellular transport". Current Opinion in Cell Biology . 11 (4): 453– 459. doi :10.1016/S0955-0674(99)80065-9 . PMID 10449330 . 1 2 "Entrez Gene: BET1 BET1 homolog (S. cerevisiae)" .
Further reading
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635– 648. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173– 1178. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Zhang T, Hong W (2001). "Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport" . The Journal of Biological Chemistry . 276 (29): 27480– 27487. doi :10.1074/jbc.M102786200 PMID 11323436 . Sanger Centre T, Washington University Genome Sequencing Cente T (November 1998). "Toward a complete human genome sequence" . Genome Research . 8 (11): 1097– 1108. doi :10.1101/gr.8.11.1097 PMID 9847074 . Hay JC, Chao DS, Kuo CS, Scheller RH (1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells" . Cell . 89 (1): 149– 158. doi :10.1016/S0092-8674(00)80191-9 PMID 9094723 . S2CID 8682509 . Hay JC, Hirling H, Scheller RH (1996). "Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus" . The Journal of Biological Chemistry . 271 (10): 5671– 5679. doi :10.1074/jbc.271.10.5671 PMID 8621431 .
