Barceloneic acid A

Barceloneic acid A
Names
Preferred IUPAC name
2-Hydroxy-6-[2-hydroxy-6-(hydroxymethyl)-4-methoxyphenoxy]-4-methylbenzoic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C16H16O7/c1-8-3-11(18)14(16(20)21)13(4-8)23-15-9(7-17)5-10(22-2)6-12(15)19/h3-6,17-19H,7H2,1-2H3,(H,20,21)
    Key: ULPVIBVOKQAXJB-UHFFFAOYSA-N
  • InChI=1/C16H16O7/c1-8-3-11(18)14(16(20)21)13(4-8)23-15-9(7-17)5-10(22-2)6-12(15)19/h3-6,17-19H,7H2,1-2H3,(H,20,21)
    Key: ULPVIBVOKQAXJB-UHFFFAOYAL
  • CC1=CC(=C(C(=C1)OC2=C(C=C(C=C2CO)OC)O)C(=O)O)O
Properties
C16H16O7
Molar mass 320.294
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Barceloneic acid A is a farnesyl transferase inhibitor isolate of Phoma.

References

  1. ↑ Jayasuriya, H; Ball, RG; Zink, DL; Smith, JL; Goetz, MA; Jenkins, RG; Nallin-Omstead, M; Silverman, KC; Bills, GF; Lingham, RB (1995). "Barceloneic acid A, a new farnesyl-protein transferase inhibitor from a Phoma species". Journal of Natural Products. 58 (7): 986–91. Bibcode:1995JNAtP..58..986J. doi:10.1021/np50121a002. PMID 7561907.