Complex network which connects several biologically relevant entities
A biological system is a complex network which connects several biologically relevant entities. Biological organization spans several scales and is determined based on different structures depending on what the system is. Examples of biological systems at the macro scale are populations of organisms. On the organ and tissue scale in mammals and other animals, examples include the circulatory system, the respiratory system, and the nervous system. On the micro to the nanoscopic scale, examples of biological systems are cells, organelles, macromolecular complexes and regulatory pathways. A biological system is not to be confused with a living system, such as a living organism.
Lymphatic system: structures involved in the transfer of lymph between tissues and the blood stream; includes the lymph and the nodes and vessels. The lymphatic system includes other functions, such as immune responses and development of antibodies.
Immune system: protects the organism from foreign bodies.
The notion of system (or apparatus) relies upon the concept of vital or organic function: a system is a set of organs with a definite function. This idea was already present in Antiquity (Galen, Aristotle), but the application of the term "system" is more recent. For example, the nervous system was named by Monro (1783), but Rufus of Ephesus (c. 90–120), clearly viewed for the first time the brain, spinal cord, and craniospinal nerves as an anatomical unit, although he wrote little about its function, nor gave a name to this unit.
The enumeration of the principal functions - and consequently of the systems - remained almost the same since Antiquity, but the classification of them has been very various, e.g., compare Aristotle, Bichat, Cuvier.
The notion of physiological division of labor, introduced in the 1820s by the French physiologist Henri Milne-Edwards, allowed to "compare and study living things as if they were machines created by the industry of man." Inspired in the work of Adam Smith, Milne-Edwards wrote that the "body of all living beings, whether animal or plant, resembles a factory ... where the organs, comparable to workers, work incessantly to produce the phenomena that constitute the life of the individual." In more differentiated organisms, the functional labor could be apportioned between different instruments or systems (called by him as appareils).
Endoplasmic reticulum: outer part of the nuclear envelope forming a continuous channel used for transportation; consists of the rough endoplasmic reticulum and the smooth endoplasmic reticulum
Rough endoplasmic reticulum (RER): considered "rough" due to the ribosomes attached to the channeling; made up of cisternae that allow for protein production
Smooth endoplasmic reticulum (SER): storage and synthesis of lipids and steroid hormones as well as detoxification
Ribosome: site of biological protein synthesis essential for internal activity and cannot be reproduced in other organs
↑F. Muggianu; A. Benso; R. Bardini; E. Hu; G. Politano; S. Di Carlo (2018). "Modeling biological complexity using Biology System Description Language (BiSDL)". 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). pp.713–717. doi:10.1109/BIBM.2018.8621533. ISBN978-1-5386-5488-0. S2CID59233194.{{cite book}}: |website= ignored (help)
12Fletcher, John (1837). "On the functions of organized beings, and their arrangement". In: Rudiments of physiology. Part 2. On life, as manifested in irritation. Edinburgh: John Carfrae & Son. pp. 1-15. link.
↑Swanson, Larry (2014). Neuroanatomical Terminology: A Lexicon of Classical Origins and Historical Foundations. Oxford: Oxford University Press. linkArchived 2023-09-28 at the Wayback Machine. p. 489.
↑Bichat, X. (1801). Anatomie générale appliquée à la physiologie et à la médecine, 4 volumes in-8, Brosson, Gabon, Paris, link. (See pp. cvj-cxj).
↑Cuvier, Georges. Lecons d'anatomie comparée 2. éd., cor. et augm. Paris: Crochard, 1835-1846. linkArchived 2009-03-02 at the Wayback Machine.
↑R. M. Brain. The Pulse of Modernism: Physiological Aesthetics in Fin-de-Siècle Europe. Seattle: University of Washington Press, 2015. 384 pp., Archived 2023-07-03 at the Wayback Machine.