CIRBP Protein-coding gene in humans
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene . The cold-inducible, RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia , and hypothermia . It is thought to be involved in DNA repair .
References
1 2 3 GRCh38: Ensembl release 89: ENSG00000099622 – Ensembl , May 20171 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045193 – Ensembl , May 2017↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ Nishiyama H, Higashitsuji H, Yokoi H, Itoh K, Danno S, Matsuda T, et al. (December 1997). "Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene". Gene . 204 (1– 2): 115– 120. doi :10.1016/S0378-1119(97)00530-1 . PMID 9434172 . ↑ Nishiyama H, Itoh K, Kaneko Y, Kishishita M, Yoshida O, Fujita J (May 1997). "A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth" . The Journal of Cell Biology . 137 (4): 899– 908. doi :10.1083/jcb.137.4.899 . PMC 2139845 PMID 9151692 . ↑ "Entrez Gene: CIRBP cold inducible RNA binding protein" .↑ Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, et al. (November 2024). "DNA repair and anti-cancer mechanisms in the long-lived bowhead whale". bioRxiv 10.1101/2023.05.07.539748
Further reading
Sheikh MS, Carrier F, Papathanasiou MA, Hollander MC, Zhan Q, Yu K, et al. (October 1997). "Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein" . The Journal of Biological Chemistry . 272 (42): 26720– 26726. doi :10.1074/jbc.272.42.26720 PMID 9334257 . Nishiyama H, Danno S, Kaneko Y, Itoh K, Yokoi H, Fukumoto M, et al. (January 1998). "Decreased expression of cold-inducible RNA-binding protein (CIRP) in male germ cells at elevated temperature" . The American Journal of Pathology . 152 (1): 289– 296. PMC 1858111 PMID 9422546 . Lee J, Bedford MT (March 2002). "PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays" . EMBO Reports . 3 (3): 268– 273. doi :10.1093/embo-reports/kvf052 . PMC 1084016 PMID 11850402 . Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proceedings of the National Academy of Sciences of the United States of America . 99 (26): 16899– 16903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Hamid AA, Mandai M, Fujita J, Nanbu K, Kariya M, Kusakari T, et al. (July 2003). "Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinoma". International Journal of Gynecological Pathology . 22 (3): 240– 247. doi :10.1097/01.PGP.0000070851.25718.EC . PMID 12819390 . S2CID 22639276 . Wellmann S, Bührer C, Moderegger E, Zelmer A, Kirschner R, Koehne P, et al. (April 2004). "Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism" . Journal of Cell Science . 117 (Pt 9): 1785– 1794. doi :10.1242/jcs.01026 PMID 15075239 . Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173– 1178. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, et al. (May 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration" . Cell . 125 (4): 801– 814. doi :10.1016/j.cell.2006.03.032 PMID 16713569 . S2CID 13709685 . Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Molecular Systems Biology . 3 (1) 89. doi :10.1038/msb4100134 . PMC 1847948 PMID 17353931 .
