CLEC11A

CLEC11A
Identifiers
Aliases	CLEC11A, CLECSF3, LSLCL, P47, SCGF, C-type lectin domain family 11 member A, C-type lectin domain containing 11A
External IDs	OMIM: 604713; MGI: 1298219; GeneCards: CLEC11A
Gene location (Human)
Chr.	Chromosome 19 (human)
End	50,725,708 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	43,956,326 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; tibia; ; periodontal fiber; ; trabecular bone; ; canal of the cervix; ; bone marrow; ; right ovary; ; left uterine tube; ; left ovary; ; right uterine tube;
	Top expressed in
	calvaria; ; body of femur; ; fossa; ; condyle; ; umbilical cord; ; molar; ; ankle; ; vestibular sensory epithelium; ; ascending aorta; ; carotid body;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	growth factor activity; carbohydrate binding;
Cellular component	cytoplasm; extracellular region; extracellular space;
Biological process	positive regulation of cell population proliferation; ossification; regulation of signaling receptor activity; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	6320
	20256
	ENSG00000105472
	ENSMUSG00000004473
	Q9Y240
	O88200
	NM_002975
	NM_009131
	NP_002966
	NP_033157
	Wikidata
View/Edit Human	View/Edit Mouse

C-type lectin domain family 11 member A is a protein that in humans is encoded by the CLEC11A gene.

Function

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000105472 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004473 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Hiraoka A, Sugimura A, Seki T, Nagasawa T, Ohta N, Shimonishi M, Hagiya M, Shimizu S (July 1997). "Cloning, expression, and characterization of a cDNA encoding a novel human growth factor for primitive hematopoietic progenitor cells". Proceedings of the National Academy of Sciences of the United States of America. 94 (14): 7577–82. Bibcode:1997PNAS...94.7577H. doi:10.1073/pnas.94.14.7577. PMC 23864. PMID 9207134.
↑ Bannwarth S, Giordanengo V, Lesimple J, Lefebvre JC (January 1998). "Molecular cloning of a new secreted sulfated mucin-like protein with a C-type lectin domain that is expressed in lymphoblastic cells". The Journal of Biological Chemistry. 273 (4): 1911–6. doi:10.1074/jbc.273.4.1911. PMID 9442024.
1 2 "Entrez Gene: CLEC11A C-type lectin domain family 11, member A".

External links

Human CLEC11A genome location and CLEC11A gene details page in the UCSC Genome Browser.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000105472 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004473 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9207134-5] Hiraoka A, Sugimura A, Seki T, Nagasawa T, Ohta N, Shimonishi M, Hagiya M, Shimizu S (July 1997). "Cloning, expression, and characterization of a cDNA encoding a novel human growth factor for primitive hematopoietic progenitor cells". Proceedings of the National Academy of Sciences of the United States of America. 94 (14): 7577–82. Bibcode:1997PNAS...94.7577H. doi:10.1073/pnas.94.14.7577. PMC 23864. PMID 9207134.

[pmid9442024-6] Bannwarth S, Giordanengo V, Lesimple J, Lefebvre JC (January 1998). "Molecular cloning of a new secreted sulfated mucin-like protein with a C-type lectin domain that is expressed in lymphoblastic cells". The Journal of Biological Chemistry. 273 (4): 1911–6. doi:10.1074/jbc.273.4.1911. PMID 9442024.

[entrez-7] 1 2 "Entrez Gene: CLEC11A C-type lectin domain family 11, member A".

CLEC11A

Function

References

Further reading

External links