CN2 may refer to:
- CN2 algorithm for rule induction
- cn|2, a weather, sports and political news cable channel owned by Time Warner Cable in former Insight Communications territories
- Optic nerve (CN2), second cranial nerve
- Cartoon Network Too, a defunct British channel owned by The WB.
- ChinaNet Next Carrying Network, one type of the Internet routes provided by China Telecom
- Cyanonitrene, molecular formula CN2
- Cyanogen, molecular formula (CN)2
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