CPNE4

CPNE4
Identifiers
Aliases	CPNE4, COPN4, CPN4, copine 4
External IDs	OMIM: 604208; MGI: 1921270; GeneCards: CPNE4
Gene location (Human)
Chr.	Chromosome 3 (human)
End	132,285,410 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	104,911,743 bp
RNA expression pattern
	Top expressed in
	lateral nuclear group of thalamus; ; myocardium of left ventricle; ; endothelial cell; ; primary visual cortex; ; Brodmann area 23; ; palpebral conjunctiva; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; Brodmann area 46; ; right ventricle;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; lumbar spinal ganglion; ; hippocampus proper; ; trigeminal ganglion; ; primary visual cortex; ; habenula; ; superior frontal gyrus; ; olfactory bulb; ; temporal lobe; ; glossopharyngeal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; calcium-dependent phospholipid binding;
Cellular component	extracellular exosome; plasma membrane;
Biological process	cellular response to calcium ion;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	131034
	74020
	ENSG00000196353
	ENSMUSG00000032564
	Q96A23; Q4G168
	Q8BLR2
	NM_001289112; NM_130808; NM_153429; NM_001388326; NM_001388327
	NM_028719; NM_001357439; NM_001378996
NP_001276041; NP_570720; NP_702907; NP_001276041.1; NP_570720.1;
	NP_702907.1
	NP_082995; NP_001344368; NP_001365925
	Wikidata
View/Edit Human	View/Edit Mouse

Copine-4 is a protein that in humans is encoded by the CPNE4 gene.

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm.

This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000196353 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032564 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Creutz CE, Tomsig JL, Snyder SL, Gautier MC, Skouri F, Beisson J, Cohen J (Feb 1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans". J Biol Chem. 273 (3): 1393–402. doi:10.1074/jbc.273.3.1393. PMID 9430674.
↑ Maitra R, Grigoryev DN, Bera TK, Pastan IH, Lee B (Apr 2003). "Cloning, molecular characterization, and expression analysis of Copine 8". Biochem Biophys Res Commun. 303 (3): 842–7. doi:10.1016/S0006-291X(03)00445-5. PMID 12670487.
1 2 "Entrez Gene: CPNE4 copine IV".

External links

Human CPNE4 genome location and CPNE4 gene details page in the UCSC Genome Browser.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000196353 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032564 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9430674-5] Creutz CE, Tomsig JL, Snyder SL, Gautier MC, Skouri F, Beisson J, Cohen J (Feb 1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans". J Biol Chem. 273 (3): 1393–402. doi:10.1074/jbc.273.3.1393. PMID 9430674.

[pmid12670487-6] Maitra R, Grigoryev DN, Bera TK, Pastan IH, Lee B (Apr 2003). "Cloning, molecular characterization, and expression analysis of Copine 8". Biochem Biophys Res Commun. 303 (3): 842–7. doi:10.1016/S0006-291X(03)00445-5. PMID 12670487.

[entrez-7] 1 2 "Entrez Gene: CPNE4 copine IV".

CPNE4

References

Further reading

External links