CPNE8

CPNE8
Identifiers
Aliases	CPNE8, copine 8
External IDs	MGI: 1914121; GeneCards: CPNE8
Gene location (Human)
Chr.	Chromosome 12 (human)
End	38,907,430 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	90,563,635 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; Achilles tendon; ; sperm; ; monocyte; ; right auricle of heart; ; testicle; ; right lung; ; retinal pigment epithelium; ; subcutaneous adipose tissue; ; right lobe of liver;
	Top expressed in
	lumbar spinal ganglion; ; lateral septal nucleus; ; epithelium of small intestine; ; seminal vesicula; ; lip; ; Region I of hippocampus proper; ; otolith organ; ; utricle; ; facial motor nucleus; ; blastocyst;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function; calcium-dependent phospholipid binding;
Cellular component	extracellular exosome; plasma membrane;
Biological process	biological process; cellular response to calcium ion;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	144402
	66871
	ENSG00000139117
	ENSMUSG00000052560
	Q86YQ8
	Q9DC53
	NM_153634
	NM_001033851; NM_025815; NM_001357979
	NP_705898
	NP_001029023; NP_080091; NP_001344908
	Wikidata
View/Edit Human	View/Edit Mouse

Copine-8 is a protein that in humans is encoded by the CPNE8 gene.

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000139117 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052560 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Maitra R, Grigoryev DN, Bera TK, Pastan IH, Lee B (Apr 2003). "Cloning, molecular characterization, and expression analysis of Copine 8". Biochem Biophys Res Commun. 303 (3): 842–847. doi:10.1016/S0006-291X(03)00445-5. PMID 12670487.
1 2 "Entrez Gene: CPNE8 copine VIII".

External links

Human CPNE8 genome location and CPNE8 gene details page in the UCSC Genome Browser.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000139117 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052560 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12670487-5] Maitra R, Grigoryev DN, Bera TK, Pastan IH, Lee B (Apr 2003). "Cloning, molecular characterization, and expression analysis of Copine 8". Biochem Biophys Res Commun. 303 (3): 842–847. doi:10.1016/S0006-291X(03)00445-5. PMID 12670487.

[entrez-6] 1 2 "Entrez Gene: CPNE8 copine VIII".

CPNE8

References

Further reading

External links