CRELD1

CRELD1
Identifiers
Aliases	CRELD1, AVSD2, CIRRIN, cysteine rich with EGF like domains 1
External IDs	OMIM: 607170; MGI: 2152539; GeneCards: CRELD1
Enzyme activity
Gene location (Human)
Chr.	Chromosome 3 (human)
End	9,945,413 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	113,470,304 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; pituitary gland; ; right lobe of thyroid gland; ; anterior pituitary; ; right uterine tube; ; apex of heart; ; right frontal lobe; ; left lobe of thyroid gland; ; primary visual cortex; ; Brodmann area 9;
	Top expressed in
	transitional epithelium of urinary bladder; ; decidua; ; dentate gyrus of hippocampal formation granule cell; ; olfactory tubercle; ; superior frontal gyrus; ; superior colliculus; ; triceps brachii muscle; ; primary visual cortex; ; central gray substance of midbrain; ; subiculum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; extracellular matrix structural constituent;
Cellular component	membrane; integral component of membrane; collagen-containing extracellular matrix;
Biological process	endocardial cushion development; cardiac septum development;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	78987
	171508
	ENSG00000163703
	ENSMUSG00000030284
	Q96HD1
	Q91XD7
	NM_001031717; NM_001077415; NM_015513
	NM_133930
NP_001026887; NP_001070883; NP_056328; NP_001361245; NP_001361246;
	NP_001361247; NP_001361248; NP_001361249
	NP_598691
	Wikidata
View/Edit Human	View/Edit Mouse

Cysteine-rich with EGF-like domain protein 1 is a protein that in humans is encoded by the CRELD1 gene.

Function

Epidermal growth factor (EGF)-like repeats are a class of cysteine-rich domains that mediate interactions between proteins of diverse function. EGF domains are found in proteins that are either completely secreted or have transmembrane regions that tether the protein to the cell surface. CRELD1 is the founding member of a family of matricellular proteins.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000163703 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030284 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Green EK, Priestley MD, Waters J, Maliszewska C, Latif F, Maher ER (Sep 2000). "Detailed mapping of a congenital heart disease gene in chromosome 3p25". J Med Genet. 37 (8): 581–7. doi:10.1136/jmg.37.8.581. PMC 1734659. PMID 10922384.
↑ Rupp PA, Fouad GT, Egelston CA, Reifsteck CA, Olson SB, Knosp WM, Glanville RW, Thornburg KL, Robinson SW, Maslen CL (Jul 2002). "Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins". Gene. 293 (1–2): 47–57. doi:10.1016/S0378-1119(02)00696-0. PMID 12137942.
1 2 "Entrez Gene: CRELD1 cysteine-rich with EGF-like domains 1".

External links

Human CRELD1 genome location and CRELD1 gene details page in the UCSC Genome Browser.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000163703 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030284 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10922384-5] Green EK, Priestley MD, Waters J, Maliszewska C, Latif F, Maher ER (Sep 2000). "Detailed mapping of a congenital heart disease gene in chromosome 3p25". J Med Genet. 37 (8): 581–7. doi:10.1136/jmg.37.8.581. PMC 1734659. PMID 10922384.

[pmid12137942-6] Rupp PA, Fouad GT, Egelston CA, Reifsteck CA, Olson SB, Knosp WM, Glanville RW, Thornburg KL, Robinson SW, Maslen CL (Jul 2002). "Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins". Gene. 293 (1–2): 47–57. doi:10.1016/S0378-1119(02)00696-0. PMID 12137942.

[entrez-7] 1 2 "Entrez Gene: CRELD1 cysteine-rich with EGF-like domains 1".

CRELD1

Function

References

Further reading

External links