CWC15

CWC15

Identifiers

CWC15, AD002, C11orf5, Cwf15, HSPC148, ORF5, CWC15 spliceosome-associated protein, CWC15 spliceosome associated protein homolog

External IDs

MGI: 1913320; GeneCards: CWC15

Gene location (Human)

Chr.	Chromosome 11 (human)

Band	11q21	Start	94,962,620 bp
Band	11q21	End	94,973,586 bp

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)

Band	9\|9 A2	Start	14,411,913 bp
Band	9\|9 A2	End	14,421,873 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

tibialis anterior muscle

cardiac muscle tissue of right atrium

myocardium of left ventricle

Skeletal muscle tissue of rectus abdominis

vastus lateralis muscle

biceps brachii

Skeletal muscle tissue of biceps brachii

body of tongue

muscle of thigh

left testis

Top expressed in

ventricular zone

neural layer of retina

muscle of thigh

morula

yolk sac

embryo

epiblast

embryo

tail of embryo

lip

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding RNA binding
Cellular component	catalytic step 2 spliceosome spliceosomal complex nucleus nucleoplasm mitochondrion nuclear speck U2-type catalytic step 2 spliceosome
Biological process	mRNA processing RNA splicing mRNA splicing, via spliceosome mRNA cis splicing, via spliceosome
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


51503


66070


ENSG00000150316


ENSMUSG00000004096


Q9P013


Q9JHS9

RefSeq (mRNA)


NM_016403 NM_001363371 NM_001363372


NM_023153

RefSeq (protein)


NP_057487 NP_001350300 NP_001350301


NP_075642

Location (UCSC)

Chr 11: 94.96 – 94.97 Mb

Chr 9: 14.41 – 14.42 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Protein CWC15 homolog is a protein that in humans is encoded by the CWC15 gene.

Interactions

CWC15 has been shown to interact with CDC5L.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000150316 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004096 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ O'Brien KP, Tapia-Paez I, Stahle-Backdahl M, Kedra D, Dumanski JP (Jul 2000). "Characterization of five novel human genes in the 11q13-q22 region". Biochem Biophys Res Commun. 273 (1): 90–4. doi:10.1006/bbrc.2000.2910. PMID 10873569.
↑ Ohi MD, Link AJ, Ren L, Jennings JL, McDonald WH, Gould KL (Mar 2002). "Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs". Mol Cell Biol. 22 (7): 2011–24. doi:10.1128/MCB.22.7.2011-2024.2002. PMC 133674. PMID 11884590.
↑ "Entrez Gene: HSPC148 hypothetical protein HSPC148".
↑ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (Dec 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529.

External links

Human CWC15 genome location and CWC15 gene details page in the UCSC Genome Browser.

Further reading

Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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