-epi-isozizaene.svg)
+ 4 reduced
ferredoxin
| Epi-isozizaene 5-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.15.39 | ||||||||
| CAS no. | 1207718-51-1 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Epi-isozizaene 5-monooxygenase (EC 1.14.15.39, CYP170A1) is an enzyme with systematic name (+)-epi-isozizaene,NADPH:oxygen oxidoreductase (5-hydroxylating). This enzyme catalyses the following overall chemical reaction:
The enzyme from Streptomyces coelicolor is an oxidoreductase which uses molecular oxygen to insert a hydroxy group into (+)-epi-isozizaene and then further oxidises that intermediate to the ketone product. It requires ferredoxin to transfer electrons to the cytochrome P450 active site.
