Catalepsy

Catalepsy
Catalepsy
SpecialtyPsychiatry, Neurology

Catalepsy (from Ancient Greek katálēpsis, κατάληψις, "seizing, grasping") is a neurological condition characterized by muscular rigidity and fixity of posture regardless of external stimuli, as well as decreased sensitivity to pain.

Signs and symptoms

A patient with depression and catalepsy
Rigidity of the body produced by catalepsy

Symptoms include a rigid body, rigid limbs, limbs staying in same position when moved (waxy flexibility), no response, loss of muscle control, and slowing down of bodily functions, such as breathing.

Causes

Catalepsy is a symptom of certain nervous disorders or conditions such as Parkinson's disease and epilepsy. It is also a characteristic symptom of cocaine withdrawal, as well as one of the features of catatonia. It can be caused by schizophrenia treatment with anti-psychotics, such as haloperidol, and by the anesthetic ketamine. Protein kinase A has been suggested as a mediator of cataleptic behavior. Unsuggested waxy catalepsy, sometimes accompanied by spontaneous anesthesia, is seen as an indicator of hypnotic trance. Suggested or induced rigid catalepsy, of extended limbs or even the entire body, sometimes tested with heavy weights, has been a staple of stage hypnosis shows and even academic demonstrations of hypnotism since the late 18th century, as proof of extraordinary physical abilities possible in trance states. Such demonstrations have also been performed by Asian martial artists and attributed to the pneumatic vital energy known as qi.[citation needed]

Historical cases

Armand D'Angour suggests that reports (such as that recounted in Plato's Symposium) of Socrates, in about 429 BC, standing perfectly still for hours on end during the Athenian campaign against Potidaea while seemingly deep in thought, are "too extreme to be considered wholly a matter of rational choice," and that "it is reasonable to suppose that it was the symptom of an underlying physiological or psychological condition", such as catalepsy.

St. Teresa of Avila experienced a prolonged bout of catalepsy that began in 1539. This episode was precipitated by the stress she experienced at the Carmelite Convent of the Incarnation. Her legs became rigid, leaving her an invalid for three years. Teresa endured intermittent attacks of catalepsy from then on.

Rufina Cambaceres, an Argentine socialite, is well known in Buenos Aires for her tragic death in 1902. The 19 year-old girl experienced a bout of catalepsy on the day of her birthday, May 31, 1902. The night of her burial in the family mausoleum, the caretaker of La Recoleta Cemetery heard noises coming from her vault. He found the coffin was not in the right position, with scratch marks on the inside of the lid and the girl's face. Rufina had been buried alive. The reason for her bout of catalepsy has never been fully clarified but it was presumed later by doctors that she died of exhaustion or shock after waking up.

Artistic depictions

In the arts, catalepsy is often used for dramatic effect, sometimes as a plot device.

Literature

Friar Laurence
...Take thou this vial, being then in bed,
And this distilléd liquor drink thou off;
When presently through all thy veins shall run
A cold and drowsy humour, for no pulse
Shall keep his native progress, but surcease:
No warmth, no breath, shall testify thou livest;
The roses in thy lips and cheeks shall fade
To paly ashes, thy eyes' windows fall,
Like death, when he shuts up the day of life;
Each part, deprived of supple government,
Shall, stiff and stark and cold, appear like death:
And in this borrow'd likeness of shrunk death
Thou shalt continue two and forty hours,
And then awake as from a pleasant sleep ...

— William Shakespeare
Romeo and Juliet
Act IV scene I

(Account of character Jem Rodney, the molecatcher)
... coming up to him he saw that Marner's eyes were set like a dead man's, and he spoke to him and shook him, and his limbs were stiff, and his hands clutched the bag as if they'd been made of iron. ... No, no; it was no stroke that would let a man stand on his legs, like a horse between the shafts, and then walk off as soon as you can say "Gee!" But there might be such a thing as a man's soul being loose from his body, and going out and in, like a bird out of its nest and back; and that was how folks got over-wise, for they went to school in this shell-less state to those who could teach them more than their neighbours could learn with their five senses and the parson.

(Narrator)
... a peculiar interest had been centred in him ever since he had fallen at a prayer meeting into a mysterious rigidity and suspension of consciousness which, lasting for an hour or more, had been mistaken for death.

— George Eliot
Silas Marner

Other media

See also

References

  1. ↑ "Definition of Catalepsy". Archived from the original on 2003-08-19. Retrieved 2008-09-18.
  2. ↑ Sanberg PR, Bunsey MD, Giordano M, Norman AB (October 1988). "The catalepsy test: its ups and downs". Behav. Neurosci. 102 (5): 748–759. doi:10.1037/0735-7044.102.5.748. PMID 2904271.
  3. ↑ Rasmussen K, Hsu MA, Noone S, Johnson BG, Thompson LK, Hemrick-Luecke SK (November 2007). "The orexin-1 antagonist SB-334867 blocks antipsychotic treatment emergent catalepsy: implications for the treatment of extrapyramidal symptoms". Schizophr Bull. 33 (6): 1291–1297. doi:10.1093/schbul/sbm087. PMC 2779883. PMID 17660489.
  4. ↑ Hattori K, Uchino S, Isosaka T, et al. (March 2006). "Fyn is required for haloperidol-induced catalepsy in mice". J. Biol. Chem. 281 (11): 7129–7135. Bibcode:2006JBiCh.281.7129H. doi:10.1074/jbc.M511608200. PMID 16407246.
  5. ↑ Miller, Ronald (2005). Miller's Anesthesia. New York: Elsevier/Churchill Livingstone. ISBN 978-0-443-06656-6.
  6. ↑ Adams MR, Brandon EP, Chartoff EH, Idzerda RL, Dorsa DM, McKnight GS (October 1997). "Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice". Proc. Natl. Acad. Sci. U.S.A. 94 (22): 12157–12161. Bibcode:1997PNAS...9412157A. doi:10.1073/pnas.94.22.12157. PMC 23735. PMID 9342379.
  7. ↑ Milton H. Erickson, edited by Ernest Rossi "Collected Papers of Milton H. Erickson", Irvington 1980
  8. ↑ D'Angour, Armand (2019). Socrates in Love. Bloomsbury Publishing, London, page 76.
  9. ↑ St. Teresa of Avila, The Life of St. Teresa de Avila, 1565, chapters V, VI, and VII.
  10. ↑ Thuras, Dylan. "The Tomb of Rufina Cambacérès in Buenos Aires". Atlas Obscura. Retrieved 2026-06-15.
  11. ↑ Hughes, T. (1972). Crow: From the Life and Songs of the Crow. London: Faber & Faber.[ISBN missing][page needed]
  12. ↑ Old Time Radio Researcher's Group https://otrr.org. Youtube: Old Time Radio, Suspense, Dead Earnest. https://www.youtube.com/watch?v=Ncb1N6InWLw or https://www.youtube.com/watch?v=YFUwDHzh2Fs