Chlorite dismutase

chlorite dismutase
Identifiers
EC no.1.13.11.49
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

Chlorite dismutase, also known as Chlorite O2-lyase (EC 1.13.11.49), is an enzyme that catalyzes the chemical reaction

ClO−2 → Cl− + O2

Reactions that generate oxygen molecules are exceedingly rare in biology, except in photosynthesis, and they are difficult to mimic synthetically. Perchlorate-respiring bacteria enzymatically detoxify chlorite (ClO−2), the end product of the perchlorate (ClO−4) respiratory pathway, by converting it to dioxygen (O2) and chloride (Cl−). Chlorite dismutase is a hemoprotein, but it bears no structural or sequence relationships with known peroxidases or other heme proteins, and is part of a large family of proteins with more than one biochemical function.

References

  1. ↑ DuBois JL, Ojha S (2015). "Chapter 3: Production of Dioxygen in the Dark: Dismutases of Oxyanions". In Kroneck PM, Torres ME (eds.). Sustaining Life on Planet Earth: Metalloenzymes Mastering Dioxygen and Other Chewy Gases. Metal Ions in Life Sciences. Vol. 15. Springer. pp. 45–87. doi:10.1007/978-3-319-12415-5_3. ISBN 978-3-319-12414-8.