Chlorophenoxy herbicide

Chemical structure of 2,4-D, the prototypical chlorophenoxy herbicide

Chlorophenoxy herbicides are a subclass of phenoxy herbicides which includes: MCPA, 2,4-D, 2,4,5-T and mecoprop. Large amounts have been produced since the 1950s for agriculture. Acute toxic effects after oral consumption are varied and may include: vomiting, abdominal pain, diarrhoea, gastrointestinal haemorrhage acutely followed by coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations and convulsions. Treatment with urinary alkalinization may be helpful but evidence to support this practice is limited.

See also

References

  1. 1 2 Roberts DM, Buckley NA (2007). "Urinary alkalinisation for acute chlorophenoxy herbicide poisoning". Cochrane Database Syst Rev (1) CD005488. doi:10.1002/14651858.CD005488.pub2. PMID 17253558.
  2. ↑ "Occupational Exposures to Chlorophenoxy Herbicides (IARC Summary & Evaluation, Volume 41, 1986)".
  3. 1 2 Bradberry SM, Proudfoot AT, Vale JA (2004). "Poisoning due to chlorophenoxy herbicides". Toxicol Rev. 23 (2): 65–73. doi:10.2165/00139709-200423020-00001. PMID 15578861.