Chrysosporide

Chrysosporide
Names
	Other names Cyclo(D-alanyl-L-leucyl-L-leucyl-D-leucyl-L-valyl)
Identifiers
CAS Number	916058-13-4 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL471885 ;
ChemSpider	17250210 ;
PubChem CID	16091636;
CompTox Dashboard (EPA)	DTXSID00582134 ;
	InChI InChI=1S/C26H47N5O5/c1-13(2)10-18-23(33)29-19(11-14(3)4)24(34)30-20(12-15(5)6)25(35)31-21(16(7)8)26(36)27-17(9)22(32)28-18/h13-21H,10-12H2,1-9H3,(H,27,36)(H,28,32)(H,29,33)(H,30,34)(H,31,35)/t17-,18+,19+,20-,21+/m1/s1 Key: IJSHLVSQYSNTII-IFLJBQAJSA-N ; InChI=1/C26H47N5O5/c1-13(2)10-18-23(33)29-19(11-14(3)4)24(34)30-20(12-15(5)6)25(35)31-21(16(7)8)26(36)27-17(9)22(32)28-18/h13-21H,10-12H2,1-9H3,(H,27,36)(H,28,32)(H,29,33)(H,30,34)(H,31,35)/t17-,18+,19+,20-,21+/m1/s1 Key: IJSHLVSQYSNTII-IFLJBQAJBN;
	SMILES O=C1N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H]1CC(C)C)CC(C)C)C)C(C)C)CC(C)C;
Properties
Chemical formula	C26H47N5O5
Molar mass	509.692 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Chrysosporide is a cyclic pentapeptide. It is isolated from the mycoparasitic fungus Sepedonium chrysospermum, found in New Zealand.

It is known that "fungi are well-known producers of a diversity of cyclic peptides with interesting structures and biological activities.... Interest in cyclic peptides is due to their significant biological activities, such as antimicrobial, insecticidal, cytotoxic, and anticancer activities, in addition to their important physiological and ecological functions."

References

↑ Mitova, Maya I.; Stuart, Blair G.; Cao, Grace H.; Blunt, John W.; Cole, Anthony L. J.; Munro, Murray H. G. (2006). "Chrysosporide, a cyclic pentapeptide from a New Zealand sample of the fungus Sepedonium chrysospermum". Journal of Natural Products. 69 (10): 1481–1484. doi:10.1021/np060137o. PMID 17067166.
↑ Jakubke, Hans-Dieter; Sewald, Norbert (2008). Peptides from A to Z: A Concise Encyclopedia. Wiley. p. 76. Retrieved 23 September 2026.
↑ Wang, Xiaohan; Lin, Minyi; Xu, Dan; Lai, Daowan; Zhou, Ligang (26 November 2017). "Structural Diversity and Biological Activities of Fungal Cyclic Peptides, Excluding Cyclodipeptides". Molecules. 22 (12): 2069. doi:10.3390/molecules22122069. PMC 6150023. Retrieved 23 September 2026.

[1] Mitova, Maya I.; Stuart, Blair G.; Cao, Grace H.; Blunt, John W.; Cole, Anthony L. J.; Munro, Murray H. G. (2006). "Chrysosporide, a cyclic pentapeptide from a New Zealand sample of the fungus Sepedonium chrysospermum". Journal of Natural Products. 69 (10): 1481–1484. doi:10.1021/np060137o. PMID 17067166.

[2] Jakubke, Hans-Dieter; Sewald, Norbert (2008). Peptides from A to Z: A Concise Encyclopedia. Wiley. p. 76. Retrieved 23 September 2026.

[3] Wang, Xiaohan; Lin, Minyi; Xu, Dan; Lai, Daowan; Zhou, Ligang (26 November 2017). "Structural Diversity and Biological Activities of Fungal Cyclic Peptides, Excluding Cyclodipeptides". Molecules. 22 (12): 2069. doi:10.3390/molecules22122069. PMC 6150023. Retrieved 23 September 2026.