
Coponius was the first Roman prefect of Judeau from 6 to 9 CE after the ethnarch of Herod Archelaus was turned into a Roman province. He oversaw the Census of Quirinius with Quirinius and the response to the revolt of Judas the Galilean.
The 1st century CE Jewish historian Josephus is the only source for Coponius.

The ethnarch kingdom of Herod Archelaus was turned into a Roman province in 6 CE and Coponius was appointed as the first person to serve as prefect of Judeau. He was, like the prefects who succeeded him, an eques, and "had the power of life and death". Coponius and Governor of Roman Syria Quirinius oversaw the Census of Quirinius in 6 CE. During his administration the revolt of Judas the Galilean occurred in response to the census. Coponius issued his own coinage.
A group of Samaritans entered the Second Temple precinct during Passover in 7 or 8 CE and scattered human bones at the portico entrance. The Temple was closed by the priests in order to purify it, resulting in celebrations being interrupted and the Temple losing revenue. Guy MacLean Rogers theorizes that Coponius' recall to Rome in 9 CE might have been connected to this incident. The Temple captain and the guards underneath him might have been created as a result of this incident; Eleazar ben Hanania, who served as Temple captain in 66 CE, helped ferment the First Jewish–Roman War. The door that the Samaritans entered through was possibly given the name "door of Coponius".
Coponius was recalled to Rome in 9 CE and replaced by Marcus Ambivulus.