Crotogoudin

Crotogoudin
Names
Other names
(+)-Crotogoudin
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C20H26O3/c1-12(2)15-6-10-19-9-5-14(13(3)17(19)22)11-20(19)18(15,4)8-7-16(21)23-20/h14-15H,1,3,5-11H2,2,4H3/t14-,15+,18+,19+,20+/m1/s1
    Key: HXJHRPFDRBBYKZ-KRUJCJHPSA-N
  • CC(=C)[C@@H]1CC[C@]23CC[C@H](C[C@]24[C@]1(CCC(=O)O4)C)C(=C)C3=O
Properties
C20H26O3
Molar mass 314.425 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Crotogoudin is a cytotoxic diterpene compound derived from the Madagascan croton plant from which crotobarin was similarly isolated. In in vitro studies, it showed antiproliferative activity against various human cancer cell lines.

References

  1. ↑ Breitler, Simon; Carreira, Erick M. (2013). "Total Synthesis of (+)-Crotogoudin". Angewandte Chemie International Edition. 52 (42): 11168–11171. doi:10.1002/anie.201305822. ISSN 1433-7851. PMID 24039092.